# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1837319 | Functional | Antiproliferative activity against human RT112 cells after 48 hrs by MTT assay | Homo sapiens | 15 | ALA1833941 | cell-based format | Scientific Literature | |
2. | ALA2050876 | Binding | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 2 uM after 48 hrs by flow cytometric analysis | 44 | ALA2046378 | cell-based format | Scientific Literature | ||
3. | ALA2050877 | Binding | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | 44 | ALA2046378 | cell-based format | Scientific Literature | ||
4. | ALA2050879 | Binding | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells after 48 hrs by flow cytometric analysis | 6 | ALA2046378 | cell-based format | Scientific Literature | ||
5. | ALA2050880 | Binding | Inhibition of ABCB1-mediated mitoxantrone efflux expressed in HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | 6 | ALA2046378 | cell-based format | Scientific Literature | ||
6. | ALA2050881 | Binding | Inhibition of ABCC1-mediated calcein transport expressed in human HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | Homo sapiens | 6 | ALA2046378 | cell-based format | Scientific Literature | |
7. | ALA2050882 | ADME | Cytotoxicity against human HEK293 cells transfected with ABCG2 up to 100 uM after 72 hrs by MTT assay | Homo sapiens | 6 | ALA2046378 | cell-based format | Scientific Literature | |
8. | ALA2050883 | ADME | Cytotoxicity against human HEK293 cells transfected with ABCG2 after 72 hrs by MTT assay | Homo sapiens | 6 | ALA2046378 | cell-based format | Scientific Literature | |
9. | ALA2050884 | ADME | Therapeutic index, ratio of IG50 for HEK293 cells to IC50 for ABCG2 | 6 | ALA2046378 | cell-based format | Scientific Literature |