# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2050876 | B | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 2 uM after 48 hrs by flow cytometric analysis | 44 | cell-based format | Scientific Literature | |||
2. | ALA2050877 | B | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | 44 | cell-based format | Scientific Literature | |||
3. | ALA2050879 | B | Inhibition of ABCG2-mediated mitoxantrone efflux expressed in HEK293 cells after 48 hrs by flow cytometric analysis | 6 | cell-based format | Scientific Literature | |||
4. | ALA2050880 | B | Inhibition of ABCB1-mediated mitoxantrone efflux expressed in HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | 6 | cell-based format | Scientific Literature | |||
5. | ALA2050881 | B | Inhibition of ABCC1-mediated calcein transport expressed in human HEK293 cells at 10 uM after 48 hrs by flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA2050882 | A | Cytotoxicity against human HEK293 cells transfected with ABCG2 up to 100 uM after 72 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA2050883 | A | Cytotoxicity against human HEK293 cells transfected with ABCG2 after 72 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA2050884 | A | Therapeutic index, ratio of IG50 for HEK293 cells to IC50 for ABCG2 | 6 | cell-based format | Scientific Literature | |||
9. | ALA1837319 | F | Antiproliferative activity against human RT112 cells after 48 hrs by MTT assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
10. | ALA1837320 | F | Cell cycle arrest in human RT112 cells by accumulation of cells at G2/M phase at 3 uM after 12 hrs by propidium iodide-staining-based flow cytometry (Rvb = 14%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA1837321 | F | Cell cycle arrest in human RT112 cells by accumulation of cells at G1 phase at 3 uM after 12 hrs by propidium iodide-staining-based flow cytometry (Rvb = 69%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA1837322 | F | Cell cycle arrest in human RT112 cells by accumulation of cells at S phase at 3 uM after 12 hrs by propidium iodide-staining-based flow cytometry (Rvb = 17%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA1837323 | F | Cell cycle arrest in human RT112 cells by accumulation of cells at G2+M phase at 3 uM after 24 hrs by propidium iodide-staining-based flow cytometry (Rvb = 14%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA1837326 | F | Induction of apoptosis in human RT112 cells assessed as hypodiploid DNA at sub-G1 phase after 48 hrs by propidium iodide-staining-based flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature |