| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1840258 | B | Selectivity ratio of IC50 for human MLK1 to IC50 for JAK2 | 1 | ALA1833803 | assay format | Scientific Literature | ||
| 2. | ALA1840259 | B | Selectivity ratio of IC50 for human ALK to IC50 for JAK2 | 1 | ALA1833803 | assay format | Scientific Literature | ||
| 3. | ALA1840260 | F | Reduction in pSTAT5 concentration in po dosed darbepoetin-stimulated C57B1/6 mouse | Mus musculus | 1 | ALA1833803 | organism-based format | Scientific Literature | |
| 4. | ALA1840261 | F | Prevention of darbepoetin-induced elevation of hematocrit in C57/BL6 mouse PV model | Mus musculus | 1 | ALA1833803 | organism-based format | Scientific Literature | |
| 5. | ALA1840262 | B | Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrate | 49 | ALA1833803 | single protein format | Scientific Literature | ||
| 6. | ALA1840263 | B | Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrate | 19 | ALA1833803 | single protein format | Scientific Literature | ||
| 7. | ALA1840264 | F | Prevention of darbepoetin-induced increase in spleen weight in C57/BL6 mouse PV model | Mus musculus | 1 | ALA1833803 | organism-based format | Scientific Literature | |
| 8. | ALA1840111 | B | Inhibition of JAK2 V617F mutant | Homo sapiens | 1 | ALA1833803 | assay format | Scientific Literature | |
| 9. | ALA1840112 | B | Inhibition of JAK2 V617F mutant-mediated STAT5 phosphorylation in mouse BAF3 cells | Homo sapiens | 1 | ALA1833803 | cell-based format | Scientific Literature | |
| 10. | ALA1840113 | B | Inhibition of JAK1 | 2 | ALA1833803 | single protein format | Scientific Literature | ||
| 11. | ALA1840117 | B | Selectivity ratio of IC50 for JAK3 to IC50 for JAK2 | 51 | ALA1833803 | assay format | Scientific Literature | ||
| 12. | ALA1840125 | B | Inhibition of human hERG | Homo sapiens | 10 | ALA1833803 | single protein format | Scientific Literature | |
| 13. | ALA1840126 | A | Inhibition of CYP3A4 at 10 uM | 10 | ALA1833803 | single protein format | Scientific Literature | ||
| 14. | ALA1840127 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 4 | ALA1833803 | organism-based format | Scientific Literature | |
| 15. | ALA1840130 | B | Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cells | 19 | ALA1833803 | cell-based format | Scientific Literature | ||
| 16. | ALA1840131 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 14 | ALA1833803 | organism-based format | Scientific Literature | |
| 17. | ALA1840132 | A | Inhibition of CYP2C9 at 10 uM | 8 | ALA1833803 | single protein format | Scientific Literature | ||
| 18. | ALA1840133 | B | Inhibition of Ikr channel | 1 | ALA1833803 | assay format | Scientific Literature | ||
| 19. | ALA1840134 | B | Inhibition of Iks channel | 1 | ALA1833803 | single protein format | Scientific Literature | ||
| 20. | ALA1840135 | B | Inhibition of rat CaV1.2 | Rattus norvegicus | 1 | ALA1833803 | single protein format | Scientific Literature |
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