# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1838642 | B | Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysis | 24 | single protein format | Scientific Literature | |||
2. | ALA1838643 | B | Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysis | 24 | single protein format | Scientific Literature | |||
3. | ALA1838644 | B | Selectivity ratio of IC50 for C-terminal full length histidine-tagged caspase-3 to IC50 for caspase-2 (amino acids 170 to 452) (unknowm origin) | 24 | assay format | Scientific Literature | |||
4. | ALA1838645 | B | Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measured up to 5 hrs by fluorometric analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
5. | ALA1838646 | B | Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measured after 48 hrs by fluorometric analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
6. | ALA1838647 | B | Ratio of IC50 for human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells to IC50 for caspase-2 (amino acids 170 to 452) | 24 | cell-based format | Scientific Literature |