# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640806 | B | Alpha adrenergic receptor activity in rat aorta | 28 | tissue-based format | Scientific Literature | |||
2. | ALA670321 | F | In vivo percent coronary flow in Mongrel dogs after administration at 3 mg/Kg (iv) | Canis lupus familiaris | 24 | organism-based format | Scientific Literature | ||
3. | ALA761866 | F | Antagonism of calcium-induced contraction of a depolarized coronary in pig | Sus scrofa | 24 | organism-based format | Scientific Literature | ||
4. | ALA766814 | B | Inhibition of human Potassium channel HERG expressed in mammalian cells | Homo sapiens | 66 | cell-based format | Scientific Literature | ||
5. | ALA781606 | F | Alpha-adrenolytic activity (pA2) on the descending thoracic branch of the rat aorta | Rattus norvegicus | 18 | organism-based format | Scientific Literature | ||
6. | ALA822598 | F | K+ channel blocking activity in human embryonic kidney cells expressing HERG Kv11.1 | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA832278 | F | Inhibition of partially open human voltage-gated potassium channel subunit Kv11.1 (ERG K+ channel) | Homo sapiens | 11 | assay format | Scientific Literature | ||
8. | ALA2071962 | A | Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
9. | ALA2071963 | A | Inhibition of human CYP2C9 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-methoxy-4-trifluoromethylcoumarin-3-acetic acid as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
10. | ALA2071964 | A | Inhibition of human CYP2C19 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 3-butyryl-7-methoxycoumarin as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
11. | ALA2071965 | A | Inhibition of human CYP2D6 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 4-methylaminoethyl-7-methoxycoumarin as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
12. | ALA2071966 | A | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using diethoxyfluorescein as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
13. | ALA2071967 | A | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-benzyloxyquinoline as substrate after 30 mins | Homo sapiens | 221 | single protein format | Scientific Literature | ||
14. | ALA2071972 | A | Covalent binding affinity to human liver microsomes assessed per mg of protein at 10 uM after 60 mins presence of NADPH | Homo sapiens | 221 | microsome format | Scientific Literature | ||
15. | ALA1909163 | B | DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) | Cavia porcellus | 871 | tissue-based format | DrugMatrix | ||
16. | ALA1909164 | B | DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) | 871 | cell membrane format | DrugMatrix | |||
17. | ALA1909165 | B | DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) | Oryctolagus cuniculus | 871 | tissue-based format | DrugMatrix | ||
18. | ALA1909166 | B | DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) | 871 | cell membrane format | DrugMatrix | |||
19. | ALA1909167 | B | DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) | 871 | cell membrane format | DrugMatrix | |||
20. | ALA1909168 | B | DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) | 871 | cell membrane format | DrugMatrix |