| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794326 | F | PUBCHEM_BIOASSAY: Detect Cellular ATP-levels in INS-1E Cells Measured in Cell-Based System Using Plate Reader - 2061-01_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 40 | cell-based format | PubChem BioAssays | ||
| 2. | ALA1794329 | F | PUBCHEM_BIOASSAY: Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-02_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 10 | cell-based format | PubChem BioAssays | ||
| 3. | ALA2014411 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as restoring cell viability after 48 hrs by luciferase based CellTiter-Glo assay | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA2014412 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as maximum activity to restoring cell viability after 48 hrs by luciferase based CellTiter-Glo assay | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA2014413 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as decrease in caspase-3 activity after 48 hrs by luminescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2014414 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as decrease in nitrite production after 48 hrs by Griess assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2014415 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as restoration of mitochondrial membrane potential at 0.25 to 5 uM after 48 hrs by JC-1 staining analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2014416 | F | Inhibition of IL-1beta, IFN-gamma and TNF-alpha-induced apoptosis of rat INS-1E cells assessed as glucose-stimulated insulin secretion at 5 uM after 48 hrs by ELISA | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1794431 | F | PUBCHEM_BIOASSAY: Primary beta islet insulin ELISA Measured in Cell-Based System Using Plate Reader - 2061-09_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 1 | cell-based format | PubChem BioAssays | ||
| 10. | ALA1794453 | F | PUBCHEM_BIOASSAY: Primary Beta Cell Apoptosis assay Measured in Cell-Based System Using Plate Reader - 2061-07_Inhibitor_Dose_DryPowder_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Homo sapiens | 1 | cell-based format | PubChem BioAssays | ||
| 11. | ALA1794472 | F | PUBCHEM_BIOASSAY: Nitrite Measured in Cell-Based System Using Plate Reader - 2061-04_Inhibitor_Dose_DryPowder_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 32 | cell-based format | PubChem BioAssays | ||
| 12. | ALA1794549 | F | PUBCHEM_BIOASSAY: Glucose-induced Insulin secretion ELISA Measured in Cell-Based System Using Plate Reader - 2061-05_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 1 | cell-based format | PubChem BioAssays | ||
| 13. | ALA1794551 | F | PUBCHEM_BIOASSAY: Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-03_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 30 | cell-based format | PubChem BioAssays | ||
| 14. | ALA1794369 | F | PUBCHEM_BIOASSAY: Nitrite Measured in Cell-Based System Using Plate Reader - 2061-04_Inhibitor_Dose_DryPowder_Activity_Set3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | Rattus norvegicus | 29 | cell-based format | PubChem BioAssays | ||
| 15. | ALA1794372 | F | PUBCHEM_BIOASSAY: Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-02_Inhibitor_Dose_DryPowder_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435007] | 7 | cell-based format | PubChem BioAssays | |||
| 16. | ALA2353844 | B | Inhibition of IFNgamma-induced JAK1/JAK2 signaling in rat INS-1E cells assessed as STAT1 nuclear translocation at 10 uM after 30 mins by immunofluorescence assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA2353845 | F | Effect on total STAT1 level in rat INS-1E cells at 10 uM after 30 mins by Western blotting analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA2353846 | B | Inhibition of JAK1/JAK2 in rat INS-1E cells assessed as inhibition of IFNgamma-induced STAT1 phosphorylation at Tyr701 and Ser727 at 10 uM after 30 mins by Western blotting analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA2353847 | P | Thermodynamic solubility in PBS at pH 7.4 after 24 hrs by UPLC-MS analysis | 10 | small-molecule physicochemical format | Scientific Literature | |||
| 20. | ALA2353848 | F | Cytoprotective activity in rat INS-1E cells assessed as suppression of cytokine-induced caspase-3/7 activation after 48 hrs by luminescence assay relative to control | Rattus norvegicus | 10 | cell-based format | Scientific Literature |
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