# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1794486 | F | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] | 10,834 | ALA1201862 | assay format | PubChem BioAssays | ||
2. | ALA2354211 | F | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line. (Class of assay: confirmatory) | 35,070 | ALA1201862 | cell-based format | PubChem BioAssays | ||
3. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
4. | ALA2354254 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) | 153,867 | ALA1201862 | assay format | PubChem BioAssays | ||
5. | ALA2354311 | F | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | 31,581 | ALA1201862 | cell-based format | PubChem BioAssays | ||
6. | ALA3624015 | B | Inhibition of G9a (unknown origin) at 50 uM by scintillation proximity assay relative to control | Homo sapiens | 27 | ALA3621101 | single protein format | Scientific Literature | |
7. | ALA3624016 | B | Inhibition of G9a (unknown origin) at 10 uM by scintillation proximity assay relative to control | Homo sapiens | 27 | ALA3621101 | single protein format | Scientific Literature | |
8. | ALA3624017 | B | Inhibition of G9a (unknown origin) at 1 uM by scintillation proximity assay relative to control | Homo sapiens | 27 | ALA3621101 | single protein format | Scientific Literature | |
9. | ALA3624018 | B | Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assay | Homo sapiens | 7 | ALA3621101 | single protein format | Scientific Literature | |
10. | ALA3624019 | P | Dissociation constant, pKa of the compound at N-1 at pH 7 by Uv-vis spectroscopy method | 27 | ALA3621101 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4262302 | F | Antiplasmodial activity against Plasmodium falciparum 3D7 after 3 days by SYBR green1 dye based assay | Plasmodium falciparum | 87 | ALA4261502 | organism-based format | Scientific Literature | |
12. | ALA4262303 | B | Inhibition of human G9a using biotinylated peptide H3( 1 to 25 residues) as substrate measured after 15 mins in presence of [3H]-SAM by scintillation proximity assay | Homo sapiens | 77 | ALA4261502 | single protein format | Scientific Literature | |
13. | ALA4262304 | T | Selectivity ratio of IC50 for human G9a to IC50 for Plasmodium falciparum 3D7 | 71 | ALA4261502 | assay format | Scientific Literature | ||
14. | ALA4262305 | A | Cytotoxicity against human HepG2 cells after 3 days by CellTiter blue assay | Homo sapiens | 87 | ALA4261502 | cell-based format | Scientific Literature | |
15. | ALA4262306 | T | Selectivity ratio of IC50 for human HepG2 cells to IC50 for Plasmodium falciparum 3D7 | 87 | ALA4261502 | assay format | Scientific Literature | ||
16. | ALA4827267 | B | Inhibition of human NSD1-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysis | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
17. | ALA4827268 | B | Inhibition of human NSD2-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysis | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
18. | ALA4827269 | B | Inhibition of human NSD3-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysis | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
19. | ALA5123980 | F | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA5120864 | cell-based format | Scientific Literature | |
20. | ALA5123981 | B | Inhibition of EHMT2 (unknown origin) | Homo sapiens | 1 | ALA5120864 | single protein format | Scientific Literature |