# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1908093 | ADME | Specific activity of expressed human recombinant UGT2B7 | Homo sapiens | 131 | ALA1907987 | single protein format | Scientific Literature | |
2. | ALA3362444 | Binding | Binding affinity to FLAG/tGFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as localization at 10 uM after 24 hrs by fluorescence microscopy | Homo sapiens | 14 | ALA3352343 | cell-based format | Scientific Literature | |
3. | ALA2423071 | Binding | Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as localization to endoplasmic reticulum and plasma membrane at 10 uM after 24 hrs by fluorescence microscopic analysis | Homo sapiens | 8 | ALA2417499 | cell-based format | Scientific Literature | |
4. | ALA2423073 | Binding | Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as protein stabilization after 24 hrs by fluorescence assay | Homo sapiens | 2 | ALA2417499 | cell-based format | Scientific Literature | |
5. | ALA4617293 | Binding | Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA4616603 | cell-based format | Scientific Literature | |
6. | ALA4617297 | Binding | Inhibition of SREBP (unknown origin) expressed in HEK293 cells assessed as reduction in LDLr promotor activity after 24 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA4616603 | cell-based format | Scientific Literature |