# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3531465 | ADME | Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS method | Homo sapiens | 16 | ALA3526014 | cell-based format | Scientific Literature | |
2. | ALA3531466 | ADME | Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS method | Homo sapiens | 16 | ALA3526014 | cell-based format | Scientific Literature | |
3. | ALA1908080 | ADME | Specific activity of expressed human recombinant UGT1A1 | Homo sapiens | 167 | ALA1907987 | single protein format | Scientific Literature | |
4. | ALA1908082 | ADME | Specific activity of expressed human recombinant UGT1A4 | Homo sapiens | 165 | ALA1907987 | single protein format | Scientific Literature | |
5. | ALA1908090 | ADME | Specific activity of expressed human recombinant UGT2B15 | Homo sapiens | 111 | ALA1907987 | single protein format | Scientific Literature | |
6. | ALA1908093 | ADME | Specific activity of expressed human recombinant UGT2B7 | Homo sapiens | 131 | ALA1907987 | single protein format | Scientific Literature | |
7. | ALA2114913 | Functional | PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) | Homo sapiens | 29,268 | ALA1201862 | assay format | PubChem BioAssays | |
8. | ALA4603181 | Binding | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction at 100 uM incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH relative to control | Homo sapiens | 13 | ALA4602613 | single protein format | Scientific Literature | |
9. | ALA4603182 | Binding | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH | Homo sapiens | 9 | ALA4602613 | single protein format | Scientific Literature | |
10. | ALA4603183 | Binding | Aggregation-based inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incubated in sodium phosphate buffer at pH 6.2 in presence of NADPH and 0.05% Triton X-100 by detergent-addition assay | Homo sapiens | 6 | ALA4602613 | single protein format | Scientific Literature | |
11. | ALA4603185 | Binding | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction pretreated with 0.3M DMSO followed by compound addition by DMSO-perturbation assay | Homo sapiens | 5 | ALA4602613 | single protein format | Scientific Literature | |
12. | ALA4603186 | Binding | Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction pretreated with 0.7M DMSO followed by compound addition by DMSO-perturbation assay | Homo sapiens | 5 | ALA4602613 | single protein format | Scientific Literature |