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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1912252 B Inhibition of GFAT-beta expressed in COS cells using N-acetylglucosamine 6-phosphate as substrate 27 cell-based format Scientific Literature 2. ALA1912253 B Noncompetitive inhibition of GFAT in presence of fructose-6-phosphate 1 single protein format Scientific Literature 3. ALA1912254 B Competitive inhibition of GFAT in presence of glutamine 1 single protein format Scientific Literature 4. ALA1912255 B Reversible inhibition of GFAT 2 single protein format Scientific Literature 5. ALA1912257 P Solubility of the compound at pH 6.4 1 small-molecule physicochemical format Scientific Literature 6. ALA1912258 P Lipophilicity, log D of the compound at pH 7.2 1 small-molecule physicochemical format Scientific Literature 7. ALA1912259 A Apparent permeability across human Caco2 cell membrane Homo sapiens 1 cell-based format Scientific Literature 8. ALA1912260 A Half life in rat at 10 mg/kg, iv Rattus norvegicus 1 organism-based format Scientific Literature 9. ALA1912261 A AUC in rat at 10 mg/kg, iv Rattus norvegicus 1 organism-based format Scientific Literature 10. ALA1912262 A Volume of distribution in rat at 10 mg/kg, iv Rattus norvegicus 1 organism-based format Scientific Literature 11. ALA1912263 A Clearance in rat at 10 mg/kg, iv Rattus norvegicus 1 organism-based format Scientific Literature 12. ALA1912264 A Tmax in rat at 50 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 13. ALA1912265 A AUC in rat at 50 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 14. ALA1912266 A Cmax in rat at 50 mg/kg, po Rattus norvegicus 1 organism-based format Scientific Literature 15. ALA1912267 A Oral bioavailability in rat at 50 mg/kg Rattus norvegicus 1 organism-based format Scientific Literature 16. ALA1912268 F Antidiabetic activity in fasted ob/ob mouse assessed as deduction of glucose excursion at 50 mg/kg, po at 4 hr and 1 hr prior to oral glucose challenge by oral glucose tolerance test Mus musculus 1 organism-based format Scientific Literature 17. ALA1912269 F Antidiabetic activity in diet-induced ob/ob mouse assessed decrease of glucose AUC at 50 mg/kg, po at 4 hr and 1 hr prior to oral glucose challenge by oral glucose tolerance test relative to control Mus musculus 1 organism-based format Scientific Literature 18. ALA1912270 P Photo-degradation of compound in DMSO at 1 mM after 2 hrs by LC/MS analysis 1 small-molecule physicochemical format Scientific Literature 19. ALA1912272 P Photo-degradation of compound in DMSO exposed to daylight at 1 mM after 24 hrs by HPLC analysis 1 small-molecule physicochemical format Scientific Literature 20. ALA1912273 P Photo-degradation of compound in solid state over years by HPLC analysis 1 small-molecule physicochemical format Scientific Literature