# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1912841 | B | Binding affinity to histidine-tagged human recombinant 14-3-3sigma by transferred NOESY analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA1912842 | B | Inhibition of 14-3-3sigma binding domain in human Ba/F3 cells expressing imatibib-sensitive wild type Bcr-Abl construct assessed as inhibition of 14-3-3sigma-c-Abl interaction | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA1912843 | B | Inhibition of 14-3-3sigma binding domain in human Ba/F3 cells expressing imatibib-resistant Bcr-Abl T315I mutant construct assessed as inhibition of 14-3-3sigma-c-Abl interaction | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA1912844 | B | Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as release of full-length c-Abl from cytoplasmic complex with 14-3-3sigma at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA1912846 | B | Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as nuclear import of full-length c-Abl at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA1912848 | B | Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as relocation of full-length c-Abl to mitochondrial membranes at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1912849 | B | Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as cleaved c-Abl at mitochondrial membranes at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique | Homo sapiens | 1 | cell-based format | Scientific Literature |