# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1918733 | Functional | Antimalarial activity against erythrocytic stage of chloroquine-sensitive Plasmodium falciparum 3D7 after 72 hrs by spectrophotometry | Plasmodium falciparum | 6 | ALA1914304 | organism-based format | Scientific Literature | |
2. | ALA1918734 | Functional | Antimalarial activity against erythrocytic stage of chloroquine-resistant Plasmodium falciparum K1 after 72 hrs by spectrophotometry | Plasmodium falciparum | 6 | ALA1914304 | organism-based format | Scientific Literature | |
3. | ALA1918735 | ADME | Cytotoxicity against human HEK293 cells after 72 hrs by luminescence assay | Homo sapiens | 173 | ALA1914304 | cell-based format | Scientific Literature | |
4. | ALA1918736 | ADME | Cytotoxicity against human Raji cells after 72 hrs by luminescence assay | Homo sapiens | 173 | ALA1914304 | cell-based format | Scientific Literature | |
5. | ALA1918737 | ADME | Cytotoxicity against human HepG2 cells after 72 hrs by luminescence assay | Homo sapiens | 173 | ALA1914304 | cell-based format | Scientific Literature | |
6. | ALA1918738 | ADME | Cytotoxicity against human BJ cells after 72 hrs by luminescence assay | Homo sapiens | 173 | ALA1914304 | cell-based format | Scientific Literature | |
7. | ALA1918739 | ADME | Selectivity ratio of EC50 for human HepG2 cells to EC50 for Plasmodium falciparum | 173 | ALA1914304 | cell-based format | Scientific Literature | ||
8. | ALA1918925 | Binding | Inhibition of human cloned ERG channel expressed in chinese hamster CHO cells after 5 mins by patch clamp assay | Homo sapiens | 5 | ALA1914304 | cell-based format | Scientific Literature | |
9. | ALA1918926 | Binding | Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as tonic inhibition after 5 mins by patch clamp assay | Homo sapiens | 4 | ALA1914304 | cell-based format | Scientific Literature | |
10. | ALA1918927 | Binding | Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as phasic inhibition after 5 mins by patch clamp assay | Homo sapiens | 4 | ALA1914304 | cell-based format | Scientific Literature | |
11. | ALA1918928 | Binding | Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assay | Homo sapiens | 4 | ALA1914304 | cell-based format | Scientific Literature | |
12. | ALA1918929 | ADME | Therapeutic index, ratio of IC50 for human ERG expressed in CHO cells to EC50 for chloroquine-resistant Plasmodium falciparum K1 | 5 | ALA1914304 | cell-based format | Scientific Literature | ||
13. | ALA1918930 | ADME | Intrinsic clearance in CD9 mouse liver microsomes by UPLC-MS analysis | Mus musculus | 7 | ALA1914304 | microsome format | Scientific Literature | |
14. | ALA1918931 | ADME | Intrinsic clearance in human liver microsomes by UPLC-MS analysis | Homo sapiens | 7 | ALA1914304 | microsome format | Scientific Literature |