| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1918733 | F | Antimalarial activity against erythrocytic stage of chloroquine-sensitive Plasmodium falciparum 3D7 after 72 hrs by spectrophotometry | Plasmodium falciparum | 6 | organism-based format | Scientific Literature | ||
| 2. | ALA1918734 | F | Antimalarial activity against erythrocytic stage of chloroquine-resistant Plasmodium falciparum K1 after 72 hrs by spectrophotometry | Plasmodium falciparum | 6 | organism-based format | Scientific Literature | ||
| 3. | ALA1918735 | A | Cytotoxicity against human HEK293 cells after 72 hrs by luminescence assay | Homo sapiens | 173 | cell-based format | Scientific Literature | ||
| 4. | ALA1918736 | A | Cytotoxicity against human Raji cells after 72 hrs by luminescence assay | Homo sapiens | 173 | cell-based format | Scientific Literature | ||
| 5. | ALA1918737 | A | Cytotoxicity against human HepG2 cells after 72 hrs by luminescence assay | Homo sapiens | 173 | cell-based format | Scientific Literature | ||
| 6. | ALA1918738 | A | Cytotoxicity against human BJ cells after 72 hrs by luminescence assay | Homo sapiens | 173 | cell-based format | Scientific Literature | ||
| 7. | ALA1918739 | A | Selectivity ratio of EC50 for human HepG2 cells to EC50 for Plasmodium falciparum | 173 | cell-based format | Scientific Literature | |||
| 8. | ALA1918925 | B | Inhibition of human cloned ERG channel expressed in chinese hamster CHO cells after 5 mins by patch clamp assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA1918926 | B | Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as tonic inhibition after 5 mins by patch clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA1918927 | B | Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as phasic inhibition after 5 mins by patch clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA1918928 | B | Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA1918929 | A | Therapeutic index, ratio of IC50 for human ERG expressed in CHO cells to EC50 for chloroquine-resistant Plasmodium falciparum K1 | 5 | cell-based format | Scientific Literature | |||
| 13. | ALA1918930 | A | Intrinsic clearance in CD9 mouse liver microsomes by UPLC-MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
| 14. | ALA1918931 | A | Intrinsic clearance in human liver microsomes by UPLC-MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 15. | ALA1918932 | A | Metabolic stability in mouse plasma over 24 hrs | Mus musculus | 3 | cell-free format | Scientific Literature | ||
| 16. | ALA1918933 | P | Chemical stability in simulated gastric fluid at pH 2 over 24 hrs | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 17. | ALA1918934 | P | Chemical stability in simulated gastric fluid at pH 5 over 24 hrs | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 18. | ALA1918935 | P | Solubility of the compound in phosphate buffered saline by UV spectrophotometry | 4 | small-molecule physicochemical format | Scientific Literature |
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