#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA663133	B	Binding energy to Streptococcus faecium dihydrofolate reductase	Enterococcus faecium	68	ALA1122106	single protein format	Scientific Literature
2.	ALA663137	B	Binding energy against Streptococcus faecium dihydrofolate reductase	Enterococcus faecium	68	ALA1121631	single protein format	Scientific Literature
3.	ALA666235	B	The concentration required to inhibit dihydrofolate reductase in rat liver		107	ALA1122689	tissue-based format	Scientific Literature
4.	ALA666236	B	Inhibitory activity against dihydrofolate reductase of rat liver		39	ALA1121851	assay format	Scientific Literature
5.	ALA666238	B	Concentration required for inhibition of rat liver dihydrofolate reductase (DHFR)		103	ALA1122259	assay format	Scientific Literature
6.	ALA3259106	F	Antimalarial activity against Plasmodium gallinaceum infected in mouse assessed as quinine equivalent to dose required to suppress parasitemia by 75% compound treated through gavage for 3 days	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
7.	ALA3259108	F	Antimalarial activity against Plasmodium gallinaceum parent strain infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
8.	ALA3252246	F	Antimalarial activity against chloroquine-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
9.	ALA3252248	F	Antimalarial activity against cycloguanil-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
10.	ALA3252250	F	Antimalarial activity against DDS-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
11.	ALA3252252	F	Antimalarial activity against chloroquine-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days relative to parent strain	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
12.	ALA3252254	F	Antimalarial activity against cycloguanil-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days relative to parent strain	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
13.	ALA3253631	F	Antimalarial activity against DDS-resistant Plasmodium gallinaceum infected in mouse assessed as dose required to suppress parasitemia by 90% compound treated through gavage for 3 days relative to parent strain	Plasmodium gallinaceum	8	ALA3244272	organism-based format	Scientific Literature
14.	ALA3280748	B	Inhibition of liver dihydrofolate reductase (unknown origin)	Homo sapiens	104	ALA3272031	assay format	Scientific Literature
15.	ALA3280522	B	Inhibition of Streptococcus faecium dihydrofolate reductase using dihydrofolate as substrate	Enterococcus faecium	66	ALA3272349	single protein format	Scientific Literature
16.	ALA3285451	F	Antimalarial activity against Plasmodium berghei infected in mouse assessed as increase in mean survival days of host at 20 mg/kg, sc administered 72 hrs after infection relative to control	Plasmodium berghei	37	ALA3272271	organism-based format	Scientific Literature
17.	ALA3285452	F	Antimalarial activity against Plasmodium berghei infected in mouse assessed as increase in mean survival days of host at 10 mg/kg, sc administered 72 hrs after infection relative to control	Plasmodium berghei	35	ALA3272271	organism-based format	Scientific Literature
18.	ALA3285693	F	Antimalarial activity against Plasmodium berghei infected in mouse assessed as increase in mean survival days of host at 5 mg/kg, sc administered 72 hrs after infection relative to control	Plasmodium berghei	23	ALA3272271	organism-based format	Scientific Literature
19.	ALA3285694	F	Antimalarial activity against Plasmodium berghei infected in mouse assessed as increase in mean survival days of host at 2.5 mg/kg, sc administered 72 hrs after infection relative to control	Plasmodium berghei	19	ALA3272271	organism-based format	Scientific Literature
20.	ALA3285695	F	Antimalarial activity against Plasmodium berghei infected in mouse assessed as increase in mean survival days of host at 1.25 mg/kg, sc administered 72 hrs after infection relative to control	Plasmodium berghei	17	ALA3272271	organism-based format	Scientific Literature