# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1918135 | B | Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
2. | ALA1918136 | F | Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after 10 mins by enzyme immunoassay | Mus musculus | 31 | cell-based format | Scientific Literature | ||
3. | ALA1918137 | F | Antagonist activity at prostanoid DP receptor in human platelet rich plasma assessed as inhibition of PGD2-induced intracellular cAMP production after 10 mins by enzyme immunoassay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
4. | ALA1918138 | P | Kinetic solubility of the compound | 7 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA1918139 | F | Inhibition of PGD2-induced vascular permeability in Hartley guinea pig conjunctiva at 0.1 mg/kg, po administered 1 hr before antigen challenge measured after 30 mins | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
6. | ALA1918180 | A | AUC (0 to infinity) in rat at 1 mg/kg, po administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
7. | ALA1918181 | A | AUC (0 to infinity) in rat at 1 mg/kg, iv administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
8. | ALA1918183 | A | Cmax in rat at 1 mg/kg, po administered as single dose | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA1918184 | A | Total clearance in rat at 1 mg/kg, iv administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA1918288 | A | Half life in rat at 1 mg/kg, iv administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA1918289 | A | Half life in rat at 1 mg/kg, po administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
12. | ALA1918290 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
13. | ALA1918291 | A | Oral bioavailability in rat at 1 mg/kg administered as single dose | Rattus norvegicus | 2 | organism-based format | Scientific Literature |