# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA706267 | Binding | Binding affinity against Lck SH2 domain | 15 | ALA1132499 | single protein format | Scientific Literature | ||
2. | ALA1037628 | Functional | Antagonist activity at human T1R2/T1R3 receptor expressed in HEK293E cells assessed as inhibition of sucralose-induced intracellular calcium mobilization | Homo sapiens | 14 | ALA1154605 | cell-based format | Scientific Literature | |
3. | ALA876466 | Physicochemical | Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system | 181 | ALA1143634 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA938588 | ADME | Binding affinity to beta cyclodextrin | 233 | ALA1140846 | assay format | Scientific Literature | ||
5. | ALA991845 | Binding | Activity at human recombinant PON1 assessed as hydrolysis of lactone ring at 1 mM by Ellman's method | Homo sapiens | 23 | ALA1155779 | single protein format | Scientific Literature | |
6. | ALA1003832 | Binding | Inhibition of tyrosin kinase pp60src | 10 | ALA1150102 | assay format | Scientific Literature | ||
7. | ALA924228 | Binding | Inhibition of aldose reductase | 28 | ALA1140501 | single protein format | Scientific Literature | ||
8. | ALA925051 | Physicochemical | Partition coefficient, log P of the compound | 68 | ALA1140614 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA925053 | ADME | Permeability across PAMPA membrane after 7 hrs | 61 | ALA1140614 | assay format | Scientific Literature | ||
10. | ALA1110921 | Functional | Antiplasmodial activity against chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 infected in human erythrocytes after 48 hrs by [3]H-hypoxanthine incorporation assay | Plasmodium falciparum | 7 | ALA1157092 | organism-based format | Scientific Literature | |
11. | ALA1110922 | ADME | Cytotoxicity against rat L6 cells after 72 hrs by alamar blue assay | Rattus norvegicus | 7 | ALA1157092 | cell-based format | Scientific Literature | |
12. | ALA1697778 | ADME | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | Homo sapiens | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
13. | ALA1697779 | ADME | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | Rodentia | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
14. | ALA1697780 | ADME | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 944 | ALA1697731 | tissue-based format | Scientific Literature | ||
15. | ALA3256049 | Physicochemical | CHCl3-water partition coefficient, log P of the compound | 60 | ALA3244276 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA3256050 | Physicochemical | Octanol-water partition coefficient, log P of the compound | 92 | ALA3244276 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA4367123 | Functional | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage assessed as reduction in multinucleated TRAP+ cells incubated for 6 days with fresh media replacement on day 3 and measured on day 6 by TRAP staining-based microscopic analysis | Mus musculus | 23 | ALA4364291 | cell-based format | Scientific Literature | |
18. | ALA4367132 | Functional | Osteo-blastogenic activity in mouse MC3T3-E1 cells assessed as stimulation of ALP activity at 10 uM supplemented with fresh medium every 3 to 4 days and measured after 14 days relative to control | Mus musculus | 22 | ALA4364291 | cell-based format | Scientific Literature | |
19. | ALA4367133 | Functional | Osteo-blastogenic activity in mouse MC3T3-E1 cells assessed as stimulation of ALP activity at 50 uM supplemented with fresh medium every 3 to 4 days and measured after 14 days relative to control | Mus musculus | 22 | ALA4364291 | cell-based format | Scientific Literature | |
20. | ALA4418320 | Functional | Inhibition of human TAS2R39 expressed in HEK293 cells coexpressing G-protein at 10 mM assessed as reduction in epicatechin gallate-induced intracellular calcium release by Fluo-4-AM dye based fluorescence assay relative to control | Homo sapiens | 36 | ALA4418259 | cell-based format | Patent Bioactivity Data |