# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1921086 | F | Agonist activity at FXR in human HepG2 cells assessed as inhibition of CYP7A1 mRNA expression at 50 uM for 6 hrs by RT-PCR relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA1921087 | F | Antiinflammatory activity in human HUVEC cells assessed as inhibition of LPS-induced IL-8 mRNA expression at 5 uM for 10 mins measured after 4 hrs of LPS challenge by Q-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA1921088 | F | Antiinflammatory activity in human HUVEC cells assessed as inhibition of TNF-alpha-induced IL-8 mRNA expression at 5 uM for 10 mins measured after 4 hrs of LPS challenge by Q-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA1921121 | F | Antiinflammatory activity in human HUVEC cells assessed as inhibition of LPS-induced E-selectin mRNA expression at 5 uM for 10 mins measured after 4 hrs of LPS challenge by Q-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA1921122 | F | Antiinflammatory activity in human HUVEC cells assessed as inhibition of TNF-alpha-induced E-selectin mRNA expression at 5 uM for 10 mins measured after 4 hrs of LPS challenge by Q-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA1921164 | F | Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
7. | ALA2209142 | F | Cytotoxicity against mouse Meth-A cells | Mus musculus | 7 | cell-based format | Scientific Literature | ||
8. | ALA2209145 | F | Cytotoxicity against mouse LLC cells | Mus musculus | 7 | cell-based format | Scientific Literature | ||
9. | ALA2208497 | F | Cytotoxicity against human HeLa cells | Homo sapiens | 45 | cell-based format | Scientific Literature |