# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1926198 | Binding | Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry | Homo sapiens | 36 | ALA1921791 | single protein format | Scientific Literature | |
2. | ALA1926199 | Functional | Anticoagulant activity in human plasma assessed as concentration required to double prothrombin-based clotting time after 30 secs using mechanical fibrometer relative to control | Homo sapiens | 24 | ALA1921791 | cell-free format | Scientific Literature | |
3. | ALA1926200 | Binding | Inhibition of human kallikrein by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
4. | ALA1926201 | Binding | Inhibition of human alpha-thrombin by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
5. | ALA1926202 | Binding | Inhibition of human tryptase expressed in baculovirus-infected insect cells by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | cell-based format | Scientific Literature | |
6. | ALA1926203 | Binding | Inhibition of human factor 10a by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
7. | ALA1926204 | Binding | Inhibition of human activated protein C by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
8. | ALA1926205 | Binding | Inhibition of human factor 11a by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
9. | ALA1926206 | Binding | Inhibition of human factor 7a by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
10. | ALA1926207 | Binding | Inhibition of human plasmin by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
11. | ALA1926208 | Binding | Inhibition of human TPA by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature | |
12. | ALA1926209 | Binding | Inhibition of human chymotrypsin by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | assay format | Scientific Literature | |
13. | ALA1926210 | Functional | Anticoagulant activity in Sprague-Dawley rat assessed as increase in prothrombin-based clotting time at 10 mg/kg, iv after 2 hrs by micro-coagulation analyzing technique relative to control | Rattus norvegicus | 1 | ALA1921791 | organism-based format | Scientific Literature | |
14. | ALA1926211 | ADME | Permeability from apical to basolateral side of human Caco2 cells at 3 uM | Homo sapiens | 8 | ALA1921791 | cell-based format | Scientific Literature | |
15. | ALA1926212 | ADME | Half life in human liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Homo sapiens | 2 | ALA1921791 | microsome format | Scientific Literature | |
16. | ALA1926213 | ADME | Half life in rat liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Rattus norvegicus | 2 | ALA1921791 | microsome format | Scientific Literature | |
17. | ALA1926214 | ADME | Half life in mouse liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Mus musculus | 2 | ALA1921791 | microsome format | Scientific Literature | |
18. | ALA1926215 | ADME | Half life in dog liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Canis lupus familiaris | 2 | ALA1921791 | microsome format | Scientific Literature | |
19. | ALA1926216 | ADME | Half life in cynomolgus monkey liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Macaca fascicularis | 2 | ALA1921791 | microsome format | Scientific Literature | |
20. | ALA1926217 | Binding | Inhibition of human u-PA by Michaelis-Menten equation analysis | Homo sapiens | 1 | ALA1921791 | single protein format | Scientific Literature |