# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1926198 | Binding | Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometry | Homo sapiens | 36 | ALA1921791 | single protein format | Scientific Literature | |
2. | ALA1926199 | Functional | Anticoagulant activity in human plasma assessed as concentration required to double prothrombin-based clotting time after 30 secs using mechanical fibrometer relative to control | Homo sapiens | 24 | ALA1921791 | cell-free format | Scientific Literature | |
3. | ALA1926211 | ADME | Permeability from apical to basolateral side of human Caco2 cells at 3 uM | Homo sapiens | 8 | ALA1921791 | cell-based format | Scientific Literature | |
4. | ALA1926212 | ADME | Half life in human liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Homo sapiens | 2 | ALA1921791 | microsome format | Scientific Literature | |
5. | ALA1926213 | ADME | Half life in rat liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Rattus norvegicus | 2 | ALA1921791 | microsome format | Scientific Literature | |
6. | ALA1926214 | ADME | Half life in mouse liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Mus musculus | 2 | ALA1921791 | microsome format | Scientific Literature | |
7. | ALA1926215 | ADME | Half life in dog liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Canis lupus familiaris | 2 | ALA1921791 | microsome format | Scientific Literature | |
8. | ALA1926216 | ADME | Half life in cynomolgus monkey liver microsomes at 0.5 uM at pH 7.4 in presence of NADPH | Macaca fascicularis | 2 | ALA1921791 | microsome format | Scientific Literature |