# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615400 | B | Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand. | 40 | ALA1123653 | assay format | Scientific Literature | ||
2. | ALA617444 | B | Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand | 42 | ALA1123653 | assay format | Scientific Literature | ||
3. | ALA785265 | F | Compound was tested for hallucinogenic activity in rats at 0.63 dose(mg/kg) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
4. | ALA785414 | F | Compound was tested for hallucinogenic activity in rats at the dose 0.16 (mg/kg) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
5. | ALA788870 | F | Ability to induce [3H]-5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-5 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
6. | ALA788871 | F | Ability to induce [3H]5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-6 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
7. | ALA788872 | F | Ability to induce [3H]5-HT release from prelabeled rat whole brain synaptosome preparations at 10e-7 M concentration | Rattus norvegicus | 5 | ALA1122159 | organism-based format | Scientific Literature | |
8. | ALA792063 | F | Compound was tested for hallucinogenic activity in rats at 0.16 dose(mg/kg); Number of rats selecting the LSDlever/ number of rats responding (1/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
9. | ALA792064 | F | Compound was tested for hallucinogenic activity in rats at 0.32 dose(mg/kg); Number of rats selecting the LSDlever/ number of rats responding (2/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
10. | ALA792884 | F | Compound was tested for hallucinogenic activity in rats at the 0.63 dose(mg/kg); Number of rats selecting the LSDlever/ number of rats responding (2/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
11. | ALA792885 | F | Compound was tested for hallucinogenic activity in rats at the 1.29 dose(mg/kg); Number of rats selecting the LSDlever/ number of rats responding (7/8) | Rattus norvegicus | 1 | ALA1123242 | organism-based format | Scientific Literature | |
12. | ALA1930561 | F | Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assay | Homo sapiens | 19 | ALA1926662 | cell-based format | Scientific Literature | |
13. | ALA1930650 | F | Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate reader | Macaca mulatta | 20 | ALA1926662 | cell-based format | Scientific Literature | |
14. | ALA4009965 | B | Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat frontal cortex membranes measured after 15 mins by scintillation counting method | Rattus norvegicus | 4 | ALA4007451 | assay format | Scientific Literature | |
15. | ALA4009966 | B | Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting method | Rattus norvegicus | 13 | ALA4007451 | subcellular format | Scientific Literature | |
16. | ALA4009967 | B | Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting method | Rattus norvegicus | 12 | ALA4007451 | subcellular format | Scientific Literature | |
17. | ALA4009968 | B | Activity at NET in rat synaptosomes assessed as release of [3H]NE after 30 mins by liquid scintillation counting method | Rattus norvegicus | 13 | ALA4007451 | subcellular format | Scientific Literature | |
18. | ALA4009970 | F | Induction of stimulus generalization in rat trained to discriminate PMMA assessed as appropriate responding level to training drug by two lever method | Rattus norvegicus | 12 | ALA4007451 | assay format | Scientific Literature |