# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1931175 | P | Chemical stability in solid state | 19 | ALA1926663 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA1931176 | P | Chemical stability in DMSO | 19 | ALA1926663 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA1931177 | P | Chemical stability in chloroform | 19 | ALA1926663 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA1931178 | P | Chemical stability in methanol | 19 | ALA1926663 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1931179 | B | Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 24 to 48 hrs | Homo sapiens | 9 | ALA1926663 | cell-based format | Scientific Literature | |
6. | ALA1931181 | A | Cytotoxicity against HGF-stimulated human MDCK cells at biologically active concentration | Homo sapiens | 7 | ALA1926663 | cell-based format | Scientific Literature | |
7. | ALA1931182 | A | Cytotoxicity against HGF-stimulated human MDCK cells at 50 to 100 fold higher biologically active concentration | Homo sapiens | 7 | ALA1926663 | cell-based format | Scientific Literature | |
8. | ALA1931183 | B | Inhibition of Met-mediated scattering in HGF-stimulated human MCF10A cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 24 to 48 hrs | Homo sapiens | 8 | ALA1926663 | cell-based format | Scientific Literature | |
9. | ALA1931184 | F | Cytotoxicity against serum-starved human HepG2 cells assessed as reduction of cell survival after 48 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 4 | ALA1926663 | cell-based format | Scientific Literature | |
10. | ALA1931185 | F | Cytotoxicity against serum-starved human GTL16 cells assessed as reduction of cell survival after 48 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 4 | ALA1926663 | cell-based format | Scientific Literature | |
11. | ALA1931186 | F | Cytotoxicity against serum-starved human BT474 cells assessed as reduction of cell survival at 10 to 30 uM after 48 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 4 | ALA1926663 | cell-based format | Scientific Literature | |
12. | ALA1931187 | F | Cytotoxicity against serum-starved human MCF7 cells over-expressing ErbB2 cells assessed as reduction of cell survival at 10 to 30 uM after 48 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 4 | ALA1926663 | cell-based format | Scientific Literature | |
13. | ALA1931188 | B | Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar growth assay | Homo sapiens | 5 | ALA1926663 | cell-based format | Scientific Literature | |
14. | ALA1931189 | B | Ratio of SU11274 IC50 to compound IC50 for inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar growth assay | Homo sapiens | 2 | ALA1926663 | cell-based format | Scientific Literature | |
15. | ALA1929610 | B | Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar growth assay | Homo sapiens | 5 | ALA1926663 | cell-based format | Scientific Literature | |
16. | ALA1929611 | B | Inhibition of TEL-fused RON-mediated mouse BA/F3 cell proliferation at 1 uM after 48 hrs by cell titre blue based spectrophotometry | 1 | ALA1926663 | single protein format | Scientific Literature | ||
17. | ALA1929612 | B | Inhibition of TPR-fused MET-mediated mouse BA/F3 cell proliferation at 1 uM after 48 hrs by cell titre blue based spectrophotometry | 1 | ALA1926663 | single protein format | Scientific Literature | ||
18. | ALA1929613 | F | Antiproliferative activity against IL3-stimulated mouse BA/F3 cells at 1 uM after 48 hrs by cell titre blue based spectrophotometry | Mus musculus | 1 | ALA1926663 | cell-based format | Scientific Literature | |
19. | ALA1929614 | B | Inhibition of HGF-induced Met phosphorylation at Tyr1234/1235 in human HepG2 cells at 10 uM pretreated overnight prior to HGF stimulation after 30 to 90 mins by Western blot analysis | Homo sapiens | 1 | ALA1926663 | cell-based format | Scientific Literature | |
20. | ALA1929615 | B | Inhibition of ErbB1 phosphorylation in human BT474 cells at 1 to 10 uM pretreated overnight prior to HGF stimulation by Western blot analysis | Homo sapiens | 1 | ALA1926663 | cell-based format | Scientific Literature |