# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1936454 | B | Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins before substrate addition measured after 5 mins by micro-plate reader analysis | Saccharomyces cerevisiae | 14 | ALA1933066 | assay format | Scientific Literature | |
2. | ALA1936455 | F | Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins | 15 | ALA1933066 | assay format | Scientific Literature | ||
3. | ALA4392653 | F | Induction of keratin-10 expression in human PHK160b cells at 50 uM incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 9 | ALA4390697 | cell-based format | Scientific Literature | |
4. | ALA4392655 | F | Induction of keratin-10 expression in human PHK160b cells incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
5. | ALA4392656 | F | Induction of keratin-1 expression in human PHK160b cells incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
6. | ALA4392657 | F | Induction of keratinocyte differentiation in human EPI-212 EpiDerm skin model assessed as increase in keratin-10 expression at 100 uM incubated for 7 days by DAB based immunohistochemical staining analysis (Rvb= 35.8%) | Homo sapiens | 1 | ALA4390697 | tissue-based format | Scientific Literature | |
7. | ALA4392658 | F | Induction of keratinocyte differentiation in human EPI-212 EpiDerm skin model assessed as increase in filaggrin expression at 100 uM incubated for 7 days by DAB based immunohistochemical staining analysis (Rvb= 20%) | Homo sapiens | 1 | ALA4390697 | tissue-based format | Scientific Literature | |
8. | ALA4392659 | A | Cytotoxicity against human PHK160b cells assessed as reduction in cell viability at 100 uM incubated for 24 hrs by MTT assay | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
9. | ALA4392661 | A | Cytotoxicity against human PHK160b cells assessed as reduction in cell viability at 10 to 1000 uM incubated for 48 hrs by LDH release assay | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
10. | ALA4392662 | F | Cell cycle arrest in human PHK160b cells assessed as accumulation at G0/G1 phase at 100 uM incubated for 48 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
11. | ALA4392663 | F | Cell cycle arrest in human PHK160b cells assessed as accumulation at G2/M phase at 100 uM incubated for 48 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
12. | ALA4392664 | F | Cell cycle arrest in human PHK160b cells assessed as increase in expression of p21 at 0 to 100 uM incubated for 72 hrs by RT-PCR method | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
13. | ALA4392665 | F | Cell cycle arrest in human PHK160b cells assessed as increase in expression of NOTCH1 at 100 uM incubated for 72 hrs by RT-PCR method relative to control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
14. | ALA4392666 | F | Cell cycle arrest in human PHK160b cells assessed as increase in expression of p21 incubated for 72 hrs by western blot method | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
15. | ALA4392667 | F | Cell cycle arrest in human PHK160b cells assessed as decrease in expression of cyclin D1 incubated for 72 hrs by western blot method | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
16. | ALA4392668 | F | Cell cycle arrest in human PHK160b cells assessed as decrease in expression of cyclin E incubated for 72 hrs by western blot method | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
17. | ALA4392669 | F | Cell cycle arrest in human PHK160b cells assessed as increase in expression of NOTCH 1 at 50 to 100 uM incubated for 72 hrs by western blot method | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
18. | ALA4392670 | F | Induction of filaggrin expression in human PHK160b cells incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
19. | ALA4392671 | F | Induction of keratin-10 expression in human PHK160b cells at 100 uM incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature | |
20. | ALA4392672 | F | Induction of keratin-1 expression in human PHK160b cells at 100 uM incubated for 48 hrs by quantitative RT-PCR analysis relative to untreated control | Homo sapiens | 1 | ALA4390697 | cell-based format | Scientific Literature |