| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4844860 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins followed by substrate addition by fluorescence based FDH-coupled assay | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 2. | ALA4844861 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins followed by alpha-KG addition after CTH addition for 2 hrs by ELISA | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA4844863 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 1 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 12 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA4844864 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 5 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 12 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4844865 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 10 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 12 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4844867 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 1 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 35 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA4844868 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 5 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 35 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA4844869 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 10 uM in presence of alpha-KG by Michaelis-Menten analysis (Rvb = 35 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4844870 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 1 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 11 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4844871 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 5 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 11 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4844872 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Km at 10 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 11 uM) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4844873 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 1 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 21 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4844874 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 5 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 21 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4844875 | B | Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 assessed as Vmax at 10 uM in presence of H3K9me3 by Michaelis-Menten analysis (Rvb = 21 /s) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4844876 | F | Cytotoxicity against human LnCaP cells assessed as growth inhibition after 48 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4844877 | F | Cytotoxicity against human DU-145 cells assessed as growth inhibition after 48 hrs by alamar blue assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4844878 | F | Cytotoxicity against human PC-3 cells assessed as growth inhibition after 48 hrs by alamar blue assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4844879 | A | Cytotoxicity against human prostate epithelial cells assessed as growth inhibition after 48 hrs by alamar blue assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4844880 | F | Cytotoxicity against human LnCaP cells assessed as remaining cell viability after 48 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4844881 | F | Cytotoxicity against human DU-145 cells assessed as remaining cell viability after 48 hrs by alamar blue assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!