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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1936263 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage after 40 mins by FRET assay | Clostridium botulinum | 29 | ALA1933027 | single protein format | Scientific Literature | |
2. | ALA1936264 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain after 40 mins by HPLC assay | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
3. | ALA1936265 | Binding | Inhibition of Bacillus anthracis lethal factor using MCA-KKVYPYPME[dnp]Kamide peptide substrate after 30 mins by FRET assay | Bacillus anthracis | 28 | ALA1933027 | single protein format | Scientific Literature | |
4. | ALA1936267 | Binding | Inhibition of Clostridium botulinum BoNT/B light chain after 40 mins by FRET-based assay | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
5. | ALA1936268 | Binding | Inhibition of human MMP1 | Homo sapiens | 2 | ALA1933027 | single protein format | Scientific Literature | |
6. | ALA1936269 | Binding | Inhibition of human MMP2 | Homo sapiens | 2 | ALA1933027 | single protein format | Scientific Literature | |
7. | ALA1936939 | Binding | Inhibition of human MMP9 | Homo sapiens | 2 | ALA1933027 | single protein format | Scientific Literature | |
8. | ALA1936940 | Binding | Inhibition of clostridium botulinum BoNT/A-mediated SNAP-25 substrate cleavage in chicken neurons at 30 uM preincubated for 15 mins before substrate addition | Clostridium botulinum | 3 | ALA1933027 | single protein format | Scientific Literature | |
9. | ALA1936941 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of zinc ion before substrate addition by FRET assay | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
10. | ALA1936942 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of glutathione before substrate addition by FRET assay | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
11. | ALA1936943 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 15 mins in presence of cysteine before substrate addition by FRET assay | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
12. | ALA1936944 | Binding | Ratio of Kinact to Ki for clostridium botulinum BoNT/A light chain | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature | |
13. | ALA1936945 | Binding | Inhibition of clostridium botulinum BoNT/A light chain assessed as residual activity using SNAP-25 as substrate at 50 uM after 90 mins measured after dialysis by FRET-based assay relative to control | Clostridium botulinum | 3 | ALA1933027 | single protein format | Scientific Literature | |
14. | ALA1936946 | Binding | Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage preincubated for 90 mins by FRET assay | Clostridium botulinum | 1 | ALA1933027 | single protein format | Scientific Literature | |
15. | ALA1936947 | Binding | Time dependent inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage by FRET assay | Clostridium botulinum | 1 | ALA1933027 | single protein format | Scientific Literature | |
16. | ALA1936948 | Binding | Inhibition of clostridium botulinum BoNT/A light chain assessed as residual activity using SNAP-25 as substrate at 50 uM after 90 mins measured after dialysis by FRET-based assay relative to 6-(4,5-dihydro-1H-imidazol-2-yl)-2-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy)phenyl)-1H-indole | Clostridium botulinum | 2 | ALA1933027 | single protein format | Scientific Literature |