# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1936805 | F | Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior to MCH-stimulation by FLIPR assay | Homo sapiens | 29 | ALA1932960 | cell-based format | Scientific Literature | |
2. | ALA1936811 | A | Clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 5 | ALA1932960 | organism-based format | Scientific Literature | |
3. | ALA1936812 | A | Mean residence time in rat at 0.5 mg/kg, iv | Rattus norvegicus | 5 | ALA1932960 | organism-based format | Scientific Literature | |
4. | ALA1936813 | A | Oral bioavailability in rat at 2 mg/kg | Rattus norvegicus | 5 | ALA1932960 | organism-based format | Scientific Literature | |
5. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | ALA3301361 | small-molecule physicochemical format | AstraZeneca Deposited Data |