# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1943215 | B | Inhibition of human MK2 | Homo sapiens | 37 | ALA1938266 | single protein format | Scientific Literature | |
2. | ALA1943216 | F | Inhibition of LPS-stimulated TNFalpha production in human THP1 cells by ELISA | Homo sapiens | 16 | ALA1938266 | cell-based format | Scientific Literature | |
3. | ALA1943217 | B | Inhibition of MK2-mediated HSP27 phosphorylation by cell-based assay | 1 | ALA1938266 | cell-based format | Scientific Literature | ||
4. | ALA1942718 | B | Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in dark using fluorescence polarization assay | 13 | ALA1938289 | single protein format | Scientific Literature | ||
5. | ALA1942719 | B | Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured after 60 mins | Homo sapiens | 13 | ALA1938289 | cell-based format | Scientific Literature | |
6. | ALA1942720 | P | Kinetic solubility of the compound at pH 7.4 | 12 | ALA1938289 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA2019904 | B | Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA assay | 26 | ALA2016522 | single protein format | Scientific Literature | ||
8. | ALA2019905 | B | Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measured after 27 mins by ELISA | Homo sapiens | 26 | ALA2016522 | cell-based format | Scientific Literature | |
9. | ALA2019906 | A | Cytotoxicity against human SW1353 cells after 30 mins by ATP-dependent luciferase luminescence assay | Homo sapiens | 26 | ALA2016522 | cell-based format | Scientific Literature | |
10. | ALA2019919 | B | Inhibition of human CK1gamma3 at 10 uM | Homo sapiens | 1 | ALA2016522 | single protein format | Scientific Literature | |
11. | ALA2019921 | A | Inhibition of CYP3A4 in human liver microsomes co-incubated with testosterone | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
12. | ALA2019922 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 30 mins prior to substrate addition | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
13. | ALA2019923 | A | Inhibition of CYP2D6 in human liver microsomes co-incubated with dextromethorphan | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
14. | ALA2019924 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 30 mins prior to substrate addition | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
15. | ALA2019981 | A | Inhibition of CYP2C9 in human liver microsomes co-incubated with tolbutamide | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
16. | ALA2019982 | A | Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate incubated for 30 mins prior to substrate addition | Homo sapiens | 1 | ALA2016522 | microsome format | Scientific Literature | |
17. | ALA2019984 | F | Antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced TNFalpha production incubated for 30 mins prior to LPS-challenge measured after 3 hrs by ELISA | Homo sapiens | 1 | ALA2016522 | cell-based format | Scientific Literature | |
18. | ALA2019985 | F | Antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL6 production incubated for 30 mins prior to LPS-challenge measured after 18 hrs by immunoabsorbent-based electrochemical luminescence assay | Homo sapiens | 1 | ALA2016522 | cell-based format | Scientific Literature | |
19. | ALA2019986 | F | Inhibition of IL1beta-stimulated MMP13 secretion in human SW1353 cells incubated for 30 mins prior to IL1beta-stimulation measured after 24 hrs by ELISA | Homo sapiens | 1 | ALA2016522 | cell-based format | Scientific Literature | |
20. | ALA2019987 | F | Inhibition of IL1beta-stimulated MMP13 secretion in human primary chondrocytes incubated for 30 mins prior to IL1beta-stimulation measured after 24 hrs by ELISA | Homo sapiens | 1 | ALA2016522 | cell-based format | Scientific Literature |