# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1941901 | B | Inhibition of N-terminal histidine-tagged PPM1Dc after 10 mins using BIOMOL GREEN assay | 1 | ALA1938369 | single protein format | Scientific Literature | ||
2. | ALA1941220 | B | Inhibition of wild-type PPM1A expressed in BL21(DE3)pLysS cells at 40 uM after 10 mins by BIOMOL GREEN assay | 1 | ALA1938369 | cell-based format | Scientific Literature | ||
3. | ALA1941221 | B | Inhibition of PP2A using Ac-DDEMT(P)GYVATR-NH2 as substrate at 40 uM after 10 mins by BIOMOL GREEN assay | 1 | ALA1938369 | assay format | Scientific Literature | ||
4. | ALA1941222 | B | Selectivity ratio for PPM1Dc over PPM1A | 1 | ALA1938369 | assay format | Scientific Literature | ||
5. | ALA1941223 | B | Inhibition of N-terminal histidine-tagged PPM1Dc at 4 uM after 10 mins by BIOMOL GREEN assay | 5 | ALA1938369 | single protein format | Scientific Literature | ||
6. | ALA1941224 | B | Inhibition of PPM1D in human MCF7 cells assessed as increase in p53 phosphorylation at Ser15 by Western blot analysis | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
7. | ALA1941225 | B | Inhibition of PPM1D in UV-irradiated human MCF7 cells assessed as increase in p53 phosphorylation at Ser15 measuring p53 protein level by Western blot analysis | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
8. | ALA1941226 | F | Antiproliferative activity against human MCF7 cells overexpressing PPM1D after 1 to 5 days by trypan blue assay | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
9. | ALA1941227 | F | Antiproliferative activity against human MCF7 cells overexpressing PPM1D at 40 uM after 1 to 5 days by trypan blue assay | Homo sapiens | 2 | ALA1938369 | cell-based format | Scientific Literature | |
10. | ALA1941228 | F | Antiproliferative activity against human A549 cells at 40 uM after 1 to 5 days by trypan blue assay | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
11. | ALA1941229 | F | Induction of cell cycle arrest in human MCF7 cells assessed as increase in accumulation at Sub-G1 phase at 40 uM after 1 day by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
12. | ALA1941230 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at Sub-G1 phase at 40 uM after 3 days by propidium iodide staining-based flow cytometry (Rvb = 9.4 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
13. | ALA1941231 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at Sub-G1 phase at 40 uM after 5 days by propidium iodide staining-based flow cytometry (Rvb = 8.1 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
14. | ALA1941232 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at G1 phase at 40 uM after 1 day by propidium iodide staining-based flow cytometry (Rvb = 45.6 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
15. | ALA1941233 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at G1 phase at 40 uM after 3 days by propidium iodide staining-based flow cytometry (Rvb = 38.5 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
16. | ALA1941234 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at G1 phase at 40 uM after 5 days by propidium iodide staining-based flow cytometry (Rvb = 57 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
17. | ALA1941235 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at S1 phase at 40 uM after 1 day by propidium iodide staining-based flow cytometry (Rvb = 24 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
18. | ALA1941236 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at S1 phase at 40 uM after 3 days by propidium iodide staining-based flow cytometry (Rvb = 29.3 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
19. | ALA1941237 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at S1 phase at 40 uM after 5 days by propidium iodide staining-based flow cytometry (Rvb = 13.8 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
20. | ALA1941238 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 40 uM after 1 day by propidium iodide staining-based flow cytometry (Rvb = 21.4 %) | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature |