| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1944187 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor ALX5407 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 2. | ALA1944188 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 1 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 3. | ALA1944189 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA1944190 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT2 inhibitor ORG25543 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 5. | ALA1944191 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM NMDA receptor glycine site antagonist L-701,324 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 6. | ALA1944192 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 7. | ALA1944193 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of GlyT1 inhibitor N-Me-SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 8. | ALA1944194 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor HPCP relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 9. | ALA1944195 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor ALX5407 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 10. | ALA1944196 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 1 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 11. | ALA1944197 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 12. | ALA1944198 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT2 inhibitor ORG25543 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA1944199 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM NMDA receptor glycine site antagonist L-701,324 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA1944200 | B | Binding affinity to GlyT1 in rat brain striatum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA1944327 | B | Binding affinity to GlyT1 in rat brain striatum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of GlyT1 inhibitor N-Me-SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 16. | ALA1944345 | B | Binding affinity to GlyT1 in rat brain midbrain at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of GlyT1 inhibitor N-Me-SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA1944346 | B | Binding affinity to GlyT1 in rat brain midbrain at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor HPCP relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 18. | ALA1944347 | B | Binding affinity to GlyT1 in rat brain midbrain at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor ALX5407 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 19. | ALA1944348 | B | Binding affinity to GlyT1 in rat brain midbrain at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 1 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 20. | ALA1944349 | B | Binding affinity to GlyT1 in rat brain midbrain at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature |
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