# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1942816 | B | Inhibition of NFkappaB-mediated ICAM1 expression in IL1alpha-stimulated human A549 cells treated 1 hr before IL1alpha challenge measured after 6 hrs by ELISA | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
2. | ALA1942817 | B | Inhibition of NFkappaB-mediated ICAM1 expression in TNFalpha-stimulated human A549 cells treated 1 hr before TNFalpha challenge measured after 6 hrs by ELISA | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA1942818 | B | Inhibition of NFkappaB-mediated ICAM1 protein expression in IL1alpha-stimulated human A549 cells preincubated for 1 hr prior IL1alpha challenge measured after 6 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
4. | ALA1942819 | A | Cytotoxicity against human A549 cells after 24 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA1942820 | A | Selectivity ratio of IC50 for human A549 cells to IC50 for NFkappaB-mediated ICAM1 expression in human A549 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
6. | ALA1942821 | A | Cytotoxicity against human A549 cells at 100 uM up to 7 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1942822 | A | Cytotoxicity against human A549 cells at 100 uM up to 7 hrs by crystal violet staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA1942823 | B | Inhibition of NF-kappaB p65 nuclear translocation in IL1alpha-stimulated human A549 cells at 30 to 100 uM incubated for 1 hr prior IL1alpha challenge measured after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA1942824 | B | Inhibition of NF-kappaB p50 nuclear translocation in IL1alpha-stimulated human A549 cells at 30 to 100 uM incubated for 1 hr prior IL1alpha challenge measured after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA1942825 | B | Inhibition of NF-kappaB p65 nuclear translocation in TNFalpha-stimulated human A549 cells at 30 to 100 uM incubated for 1 hr prior TNFalpha challenge measured after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA1942910 | B | Inhibition of NF-kappaB p50 nuclear translocation in TNFalpha-stimulated human A549 cells at 30 to 100 uM incubated for 1 hr prior TNFalpha challenge measured after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA1943294 | F | Inhibition of IL1alpha-induced IkappaBalpha degradation in human A549 cells at 100 uM incubated for 1 hr prior IL1alpha challenge measured after 15 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
13. | ALA1943295 | F | Inhibition of TNF-alpha-induced IkappaBalpha degradation in human A549 cells at 100 uM incubated for 1 hr prior TNFalpha challenge measured after 15 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA1943296 | B | Inhibition of IL1alpha-induced IkappaBalpha phosphorylation in human A549 cells at 10 to 100 uM incubated for 1 hr prior to IL1alpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA1943297 | B | Inhibition of TNF-alpha-induced IkappaBalpha phosphorylation in human A549 cells at 10 to 100 uM incubated for 1 hr prior to TNFalpha challenge measured after 15 mins by Western blot analysis in the presence of proteasome inhibitor MG-132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA1943300 | A | Cytotoxicity against human A549 cells at 100 to 320 uM after 24 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA1943301 | B | Inhibition of NFkappaB-mediated ICAM1 protein expression in TNFalpha-stimulated human A549 cells preincubated for 1 hr prior TNFalpha challenge measured after 6 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
18. | ALA4395598 | B | Inhibition of ICAM-1 in human A549 cells after 1 hr in presence of IL-1beta | Homo sapiens | 1 | cell-based format | Scientific Literature |