| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1947960 | B | Inhibition of N-terminus His-tagged Francisella tularensis subsp. Tularensis Schu4 Fab1 expressed in Escherichia coli DL21 (DE3) cells assessed as conversion of crotonyl-CoA and NADH to butyryl-CoA and NAD+ preincubated for 30 mins by measured fluorescence analysis | Francisella tularensis subsp. tularensis SCHU S4 | 18 | ALA1944564 | cell-based format | Scientific Literature | |
| 2. | ALA1947961 | F | Antibacterial activity against Escherichia coli BW251113 after overnight incubation | Escherichia coli | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 3. | ALA1947962 | F | Antibacterial activity against Escherichia coli BW251113 harboring TolC deletion mutation after overnight incubation | Escherichia coli | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 4. | ALA1947963 | F | Antibacterial activity against Francisella tularensis after overnight incubation | Francisella tularensis | 5 | ALA1944564 | assay format | Scientific Literature | |
| 5. | ALA1947964 | F | Antibacterial activity against Bacillus anthracis after overnight incubation | Bacillus anthracis | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 6. | ALA1947965 | F | Antibacterial activity against Yersinia pestis after overnight incubation | Yersinia pestis | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 7. | ALA1947966 | F | Antibacterial activity against Staphylococcus aureus after overnight incubation | Staphylococcus aureus | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 8. | ALA1947967 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus after overnight incubation | Staphylococcus aureus | 5 | ALA1944564 | organism-based format | Scientific Literature | |
| 9. | ALA1947968 | F | Ratio of MIC for Escherichia coli BW251113 to MIC for Escherichia coli BW251113 harboring TolC deletion mutation | Escherichia coli | 1 | ALA1944564 | organism-based format | Scientific Literature | |
| 10. | ALA2156467 | B | Inhibition of Francisella tularensis subsp. tularensis SCHU4 N-terminal His-tagged FabI-NADH complex expressed in Escherichia coli BL21(DE3) using crotonyl-CoA as substrate in presence of 200 uM NAD+ | Francisella tularensis subsp. tularensis SCHU S4 | 1 | ALA2151032 | assay format | Scientific Literature | |
| 11. | ALA2156468 | B | Competitive inhibition of Francisella tularensis subsp. tularensis SCHU4 N-terminal His-tagged FabI expressed in Escherichia coli BL21(DE3) using crotonyl-CoA as substrate by Dixon plot analysis in presence of 200 uM NADH | Francisella tularensis subsp. tularensis SCHU S4 | 1 | ALA2151032 | assay format | Scientific Literature | |
| 12. | ALA2156469 | B | Uncompetitive inhibition of Francisella tularensis subsp. tularensis SCHU4 N-terminal His-tagged FabI expressed in Escherichia coli BL21(DE3) using NADH as substrate by Dixon plot analysis in presence of 500 uM crotonyl-CoA | Francisella tularensis subsp. tularensis SCHU S4 | 1 | ALA2151032 | assay format | Scientific Literature | |
| 13. | ALA3118186 | A | Cytotoxicity against human PC3 cells at 10 uM after 96 hrs by luciferase reporter gene assay | Homo sapiens | 3 | ALA3112563 | cell-based format | Scientific Literature | |
| 14. | ALA3118187 | A | Cytotoxicity against HFF assessed as cell viability at 10 uM after 72 hrs by WST-1 assay | Homo sapiens | 3 | ALA3112563 | cell-based format | Scientific Literature | |
| 15. | ALA3118188 | F | Antiparasitic activity against tachyzoite stage of Toxoplasma gondii PRU infected in HFF assessed as inhibition of parasite growth at 10 uM after 72 hrs by yellow fluorescence reporter gene assay | Toxoplasma gondii | 2 | ALA3112563 | assay format | Scientific Literature | |
| 16. | ALA3118189 | F | Antiparasitic activity against tachyzoite stage of Toxoplasma gondii RH infected in HFF assessed as inhibition of parasite growth after 72 hrs by yellow fluorescence reporter gene assay | Toxoplasma gondii | 3 | ALA3112563 | organism-based format | Scientific Literature | |
| 17. | ALA3118190 | B | Inhibition of Toxoplasma gondii enoyl-ACP reductase-NADH complex | Toxoplasma gondii | 3 | ALA3112563 | single protein format | Scientific Literature | |
| 18. | ALA3399070 | B | Inhibition of N-terminus His-tagged Francisella tularensis subsp. Tularensis Schu4 Fab1 expressed in Escherichia coli DL21 (DE3) cells assessed as conversion of crotonyl-CoA and NADH to butyryl-CoA and NAD+ preincubated for 30 mins by fluorescence analysis | Francisella tularensis subsp. tularensis SCHU S4 | 10 | ALA3396952 | cell-based format | Scientific Literature | |
| 19. | ALA3399071 | F | Antimicrobial activity against Francisella tularensis Utah 112 measured after overnight incubation by microdilution method | Francisella tularensis | 10 | ALA3396952 | assay format | Scientific Literature | |
| 20. | ALA3399072 | F | Antimicrobial activity against Staphylococcus aureus ATCC 29213 measured after overnight incubation by microdilution method | Staphylococcus aureus | 10 | ALA3396952 | organism-based format | Scientific Literature |
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