# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1953150 | Binding | Displacement of [3H]LSD from human recombinant 5HT6 receptor | Homo sapiens | 21 | ALA1949541 | single protein format | Scientific Literature | |
2. | ALA1953151 | Binding | Displacement of [3H]LSD from rat recombinant 5HT6 receptor | Rattus norvegicus | 10 | ALA1949541 | single protein format | Scientific Literature | |
3. | ALA1953152 | Functional | Antagonist activity at human 5HT6 receptor expressed in human astrocytoma cells assessed as inhibition of cAMP production | Homo sapiens | 14 | ALA1949541 | cell-based format | Scientific Literature | |
4. | ALA1953155 | ADME | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA1949541 | organism-based format | Scientific Literature | |
5. | ALA1953156 | ADME | Plasma clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA1949541 | organism-based format | Scientific Literature | |
6. | ALA1953157 | ADME | Volume of distribution in rat at 1 mg/kg, iv | Rattus norvegicus | 2 | ALA1949541 | organism-based format | Scientific Literature | |
7. | ALA1953158 | ADME | Oral bioavailability in rat at 5 mg/kg at 24 hrs | Rattus norvegicus | 2 | ALA1949541 | organism-based format | Scientific Literature | |
8. | ALA1953159 | ADME | Ratio of drug uptake in brain to plasma in rat at 5 mg/kg, po | Rattus norvegicus | 2 | ALA1949541 | organism-based format | Scientific Literature | |
9. | ALA1953160 | Physicochemical | Aqueous solubility at pH 7.4 | 1 | ALA1949541 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA1953161 | Physicochemical | Aqueous solubility at pH 2 | 1 | ALA1949541 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA1953162 | ADME | Apparent permeability from apical to basal side of MDCK2-MDR1 | Canis lupus familiaris | 1 | ALA1949541 | cell-based format | Scientific Literature | |
12. | ALA1953163 | ADME | Efflux ratio of apparent permeability across MDCK2-MDR1 cells | Canis lupus familiaris | 1 | ALA1949541 | cell-based format | Scientific Literature | |
13. | ALA1953164 | ADME | Plasma protein binding in rat | Rattus norvegicus | 1 | ALA1949541 | cell-free format | Scientific Literature | |
14. | ALA1953165 | ADME | Plasma protein binding in human | Homo sapiens | 1 | ALA1949541 | cell-free format | Scientific Literature | |
15. | ALA1953166 | ADME | Half life in mouse liver microsomes | Mus musculus | 3 | ALA1949541 | microsome format | Scientific Literature | |
16. | ALA1953167 | ADME | Half life in rat liver microsomes | Rattus norvegicus | 3 | ALA1949541 | microsome format | Scientific Literature | |
17. | ALA1953168 | ADME | Half life in dog liver microsomes | Canis lupus familiaris | 3 | ALA1949541 | microsome format | Scientific Literature | |
18. | ALA1953169 | ADME | Half life in human liver microsomes | Homo sapiens | 3 | ALA1949541 | microsome format | Scientific Literature | |
19. | ALA1953170 | ADME | Inhibition of CYP 1A2 | 1 | ALA1949541 | single protein format | Scientific Literature | ||
20. | ALA1953171 | ADME | Inhibition of CYP 2C9 | 1 | ALA1949541 | single protein format | Scientific Literature |