| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1954477 | F | Antagonist activity at rat recombinant GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 2. | ALA1954478 | F | Antagonist activity rat recombinant GluN1/GluN2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 3. | ALA1954479 | F | Antagonist activity rat recombinant GluN1/GluN2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 4. | ALA1954480 | F | Antagonist activity rat recombinant GluN1/GluN2D receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 5. | ALA1954481 | F | Antagonist activity at rat recombinant GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response at 100 uM by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 3 | ALA1949555 | cell-based format | Scientific Literature | |
| 6. | ALA1954482 | F | Antagonist activity rat recombinant GluN1/GluN2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response at 100 uM by two-electrode voltage-clamp electrophysiology assay | Rattus norvegicus | 4 | ALA1949555 | cell-based format | Scientific Literature | |
| 7. | ALA1954485 | F | Antagonist activity at human recombinant GluK1 receptor expressed in human HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by fluorescence assay | Homo sapiens | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 8. | ALA1954486 | F | Antagonist activity at human recombinant GluK2 receptor expressed in human HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by fluorescence assay | Homo sapiens | 25 | ALA1949555 | cell-based format | Scientific Literature | |
| 9. | ALA1954487 | B | Selectivity ratio of Ki(app) for rat recombinant GluN1/GluN2A receptor to Ki(app) for rat recombinant GluN1/GluN2D receptor | Rattus norvegicus | 5 | ALA1949555 | assay format | Scientific Literature | |
| 10. | ALA1954488 | B | Selectivity ratio of Ki(app) for rat recombinant GluN1/GluN2B receptor to Ki(app) for rat recombinant GluN1/GluN2D receptor | Rattus norvegicus | 3 | ALA1949555 | assay format | Scientific Literature | |
| 11. | ALA1954491 | P | Solubility of the compound in water at >100 uM | 2 | ALA1949555 | small-molecule physicochemical format | Scientific Literature |
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