| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1954505 | B | Displacement of [3H]17betaE2 from human N-His6-tagged ERbeta ligand binding domain expressed in Escherichia coli BL21 cells by radiometric assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 2. | ALA1954506 | B | Displacement of [3H]17betaE2 from human N-His6-tagged ERalpha ligand binding domain expressed in Escherichia coli BL21 cells by radiometric assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 3. | ALA1954670 | B | Selectivity ratio of binding affinity to human N-His6-tagged human ERbeta relative to estradiol to binding affinity for human N-His6-tagged ERalpha relative to estradiol | Homo sapiens | 3 | ALA1949571 | assay format | Scientific Literature | |
| 4. | ALA1954671 | B | Agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERbeta ligand binding domain expressed in Escherichia coli BL21 cells after 1 hr by TR-FRET assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 5. | ALA1954672 | B | Agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERbeta ligand binding domain expressed in Escherichia coli BL21 cells after 1 hr by TR-FRET assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 6. | ALA1954673 | B | Agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERalpha ligand binding domain expressed in Escherichia coli BL21 cells after 1 hr by TR-FRET assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 7. | ALA1954674 | B | Agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERalpha ligand binding domain expressed in Escherichia coli BL21 cells after 1 hr by TR-FRET assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 8. | ALA1954675 | F | Selectivity ratio of agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERbeta LBD relative to estradiol to agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERalpha LBD relative to estradiol | Homo sapiens | 3 | ALA1949571 | assay format | Scientific Literature | |
| 9. | ALA1954676 | B | Agonist activity at human N-His6-tagged terbium-labelled ERbeta ligand binding domain expressed in Escherichia coli BL21 cells assessed as recruitment of fluorescein-labelled SRC3 after 1 hr by TR-FRET assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 10. | ALA1954677 | B | Agonist activity at human N-His6-tagged terbium-labelled ERbeta ligand binding domain expressed in Escherichia coli BL21 cells assessed as recruitment of fluorescein-labelled SRC3 after 1 hr by TR-FRET assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 11. | ALA1954678 | B | Agonist activity at human N-His6-tagged terbium-labelled ERalpha ligand binding domain expressed in Escherichia coli BL21 cells assessed as recruitment of fluorescein-labelled SRC3 after 1 hr by TR-FRET assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 12. | ALA1954679 | B | Agonist activity at human N-His6-tagged terbium-labelled ERalpha ligand binding domain expressed in Escherichia coli BL21 cells assessed as recruitment of fluorescein-labelled SRC3 after 1 hr by TR-FRET assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 13. | ALA1954680 | F | Selectivity ratio of agonist activity at human N-His6-tagged terbium-labelled human ERbeta relative to estradiol to agonist activity at human N-His6-tagged terbium-labelled ERalpha relative to estradiol assessed as recruitment of fluorescein-labelled SRC3 | Homo sapiens | 3 | ALA1949571 | assay format | Scientific Literature | |
| 14. | ALA1954681 | F | Agonist activity at human ERbeta expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 15. | ALA1954682 | F | Agonist activity at human ERbeta expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 16. | ALA1954683 | F | Agonist activity at human ERalpha expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 17. | ALA1954160 | F | Agonist activity at human ERalpha expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 18. | ALA1954161 | F | Selectivity ratio of agonist activity at human ERbeta expressed in HEC-1 cells relative to estradiol to agonist activity at human ERalpha expressed in HEC-1 cells relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature | |
| 19. | ALA1954162 | F | Agonist activity at human ERbeta expressed in U2OS cells coexpressing pCMX-hSRC3 assessed as luciferase activity after 24 hrs by reporter gene assay | Homo sapiens | 4 | ALA1949571 | cell-based format | Scientific Literature | |
| 20. | ALA1954163 | F | Agonist activity at human ERbeta expressed in U2OS cells coexpressing pCMX-hSRC3 assessed as luciferase activity after 24 hrs by reporter gene assay relative to estradiol | Homo sapiens | 3 | ALA1949571 | cell-based format | Scientific Literature |
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