# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1953328 | Functional | Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay | Mus musculus | 1 | ALA1949667 | cell-based format | Scientific Literature | |
2. | ALA2399320 | Functional | Antitumor activity against MEF harboring KRAS G12D mutant allografted in p53-null mouse assessed as reduction in tumor weight relative to control | Mus musculus | 1 | ALA2396593 | cell-based format | Scientific Literature | |
3. | ALA2399321 | Functional | Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay | Mus musculus | 1 | ALA2396593 | cell-based format | Scientific Literature | |
4. | ALA2399322 | Functional | Antitumor activity against MEF harboring KRAS G12D mutant allografted in p53-null mouse assessed as reduction in tumor volume relative to control | Mus musculus | 1 | ALA2396593 | cell-based format | Scientific Literature | |
5. | ALA5250660 | Functional | Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay | Mus musculus | 1 | ALA5247631 | cell-based format | Scientific Literature | |
6. | ALA5250661 | Functional | Antitumor activity against mouse MEF cells xenografted in nude mouse assessed as reduction in tumor weight at 40 mg/kg, po twice daily for 7 days relative to control | Mus musculus | 1 | ALA5247631 | organism-based format | Scientific Literature |