# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1953213 | F | Antiviral activity against Rotavirus SA11 in MA104 cells assessed as inhibition of viral replication after 24 hrs by immunofluorescent assay and Western blotting analysis | Rotavirus | 14 | ALA1949627 | organism-based format | Scientific Literature | |
2. | ALA1953214 | F | Antiviral activity against Rotavirus Wa in MA104 cells assessed as inhibition of viral replication after 24 hrs by immunofluorescent assay and Western blotting analysis | Rotavirus | 6 | ALA1949627 | organism-based format | Scientific Literature | |
3. | ALA1953215 | A | Cytotoxicity against monkey MA104 cells after 24 hrs | Macaca mulatta | 14 | ALA1949627 | cell-based format | Scientific Literature | |
4. | ALA1953216 | A | Therapeutic index, ratio of TD50 for monkey MA104 cells to ED50 for Rotavirus SA11 | 2 | ALA1949627 | cell-based format | Scientific Literature | ||
5. | ALA1953217 | F | Virucidal activity against Rotavirus SA11 in MA104 cells assessed as reduction in viral titer at 100 uM pretreated for 2 hrs prior infection measured after 12 hrs postinfection by immunofluorescent assay | Rotavirus | 2 | ALA1949627 | organism-based format | Scientific Literature | |
6. | ALA1953218 | F | Virucidal activity against Rotavirus SA11 in MA104 cells assessed as reduction in viral titer at 100 uM pretreated for 2 hrs prior infection measured after 12 hrs postinfection by Western blotting analysis | Rotavirus | 2 | ALA1949627 | organism-based format | Scientific Literature | |
7. | ALA1953219 | F | Inhibition of lipogenesis in monkey MA104 cells infected with Rotavirus SA11 assessed as inhibition of increase in lipid droplets at 1 uM after 10 hrs by NBD-cholesterol based fluorescence analysis | Macaca mulatta | 3 | ALA1949627 | cell-based format | Scientific Literature | |
8. | ALA1953220 | F | Inhibition of lipogenesis in human HuH7 cells assessed as inhibition of increase in lipid droplets at 1 uM after 72 hrs by NBD-cholesterol based fluorescence analysis | Homo sapiens | 3 | ALA1949627 | cell-based format | Scientific Literature | |
9. | ALA3118815 | F | Effect on mean extractable lipid mass in mouse bEND.3 cells at 15 uM relative to control | Mus musculus | 6 | ALA3112439 | cell-based format | Scientific Literature | |
10. | ALA3118817 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell extravasation in unbranched post-capillary venules of mesentery at 50 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
11. | ALA3118818 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell extravasation in unbranched post-capillary venules of mesentery at 5 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
12. | ALA3118819 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell adhesion in unbranched post-capillary venules of mesentery at 50 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
13. | ALA3118820 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell adhesion in unbranched post-capillary venules of mesentery at 5 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
14. | ALA3118821 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell rolling in unbranched post-capillary venules of mesentery at 50 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
15. | ALA3118822 | F | Inhibition of Sprague-Dawley rat leukocytes recruitment assessed as inhibition of cell rolling in unbranched post-capillary venules of mesentery at 5 uM measured at 120 mins | Rattus norvegicus | 2 | ALA3112439 | tissue-based format | Scientific Literature | |
16. | ALA3118823 | B | Inhibition of ACSL in mouse solubilized bEND.3 cells using [14C]-palmitic acid as substrate assessed as effect on total recovery of radioactive substrate at 15 uM after 2 hrs by liquid scintillation spectrometric analysis | Mus musculus | 5 | ALA3112439 | assay format | Scientific Literature | |
17. | ALA3118824 | B | Inhibition of ACSL in mouse solubilized bEND.3 cells using [14C]-palmitic acid as substrate assessed as decrease in radioactivity in aqueous layer at 15 uM after 2 hrs by liquid scintillation spectrometric analysis | Mus musculus | 6 | ALA3112439 | assay format | Scientific Literature | |
18. | ALA3118825 | B | Inhibition of ACSL in mouse solubilized bEND.3 cells using [14C]-palmitic acid as substrate assessed as increase in unincorporated radioactivity in media at 15 uM after 2 hrs by liquid scintillation spectrometric analysis | Mus musculus | 6 | ALA3112439 | assay format | Scientific Literature | |
19. | ALA3118826 | B | Inhibition of ACSL in mouse solubilized bEND.3 cells assessed as inhibition of [14C]-palmitate incorporation into extractable lipids at 15 uM after 2 hrs by liquid scintillation spectrometric analysis | Mus musculus | 6 | ALA3112439 | assay format | Scientific Literature | |
20. | ALA3118827 | B | Inhibition of ACSL in mouse solubilized bEND.3 cells using [14C]-palmitic acid as substrate after 2 mins by liquid scintillation spectrometric analysis | Mus musculus | 13 | ALA3112439 | assay format | Scientific Literature |