| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2034623 | B | Activity of N-terminus hexaHis-tagged human TNSK2 expressed in Escherichia coli BL21 (DE3) cells using biotinylated NAD+ as substrate after 90 mins by Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA1960316 | B | Inhibition of beta-casein-dependent canonical Wnt3A pathway in human HEK293T cells at 1 uM by luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA1960317 | B | Inhibition of beta-casein-dependent canonical Wnt3 pathway in human HEK293T cells by luciferase reporter gene assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 4. | ALA1960320 | F | Cardiogenic activity in human H9 cells after 14 days by MYH6-mCherry reporter gene assay relative to 4-[(1R,2S,6R,7S)-3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl]-N-quinolin-8-ylbenzamide | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 5. | ALA4003515 | B | Inhibition of PARP12 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 6. | ALA4003516 | B | Inhibition of PARP14 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 7. | ALA4003517 | B | Inhibition of full length recombinant human N-terminal GST-tagged PARP1 expressed in Baculovirus infected Sf9 cells using TACS-Sapphire as substrate measured after 1 hr by colorimetric assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA4003518 | B | Inhibition of recombinant human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells measured after 1 hr by chemiluminescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4003519 | B | Inhibition of PARP3 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 10. | ALA4003520 | B | Inhibition of PARP4 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 11. | ALA4003521 | B | Inhibition of recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using TACS-Sapphire as substrate measured after 30 mins by colorimetric assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4003522 | B | Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated NAD+ as substrate measured after 2 hrs | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4003523 | B | Inhibition of PARP10 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 14. | ALA4003524 | B | Inhibition of PARP15 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 15. | ALA4003525 | B | Inhibition of PARP16 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 16. | ALA4003535 | B | Selectivity ratio of IC50 for PARP1 (unknown origin) to IC50 for TNKS2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4003536 | B | Selectivity ratio of IC50 for PARP2 (unknown origin) to IC50 for TNKS2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4003539 | B | Selectivity ratio of IC50 for full length recombinant human N-terminal GST-tagged PARP1 expressed in Baculovirus infected Sf9 cells to IC50 for recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4003540 | B | Selectivity ratio of IC50 for recombinant human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in Baculovirus infected Sf9 cells to IC50 for recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4003541 | B | Inhibition of TNKS2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature |
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