# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1959960 | Functional | Cytotoxicity against human Calu6 cells expressing VIPR1 up to 10 uM in presence of 2% serum | Homo sapiens | 20 | ALA1955783 | cell-based format | Scientific Literature | |
2. | ALA1959961 | Functional | Cytotoxicity against human NCI-H1299 cells expressing VIPR1 up to 10 uM in presence of 2% serum | Homo sapiens | 20 | ALA1955783 | cell-based format | Scientific Literature | |
3. | ALA1959962 | Functional | Cytotoxicity against human NCI-H727 cells expressing VIPR1 up to 10 uM in presence of 2% serum | Homo sapiens | 20 | ALA1955783 | cell-based format | Scientific Literature | |
4. | ALA1960401 | Binding | Displacement of [125I]VIP from vasoactive intestinal peptide receptor 1 in rat RKE cell membrane after 3 hrs by TopCount assay | Rattus norvegicus | 43 | ALA1955783 | cell-based format | Scientific Literature | |
5. | ALA1960402 | Functional | Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulation incubated for 10 mins prior to VIP-stimulation measured after 30 mins by HTRF assay | Rattus norvegicus | 43 | ALA1955783 | cell-based format | Scientific Literature |