| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1960797 | F | Antiparasitic activity against hypoxanthine-guanine-xanthine phosphoribosyltransferase gene knock out Toxoplasma gondii expressing Cryptosporidium parvum IMPDH infected in human foreskin fibroblasts assessed as parasite proliferation by fluorescence assay | Toxoplasma gondii | 5 | organism-based format | Scientific Literature | ||
| 2. | ALA1960800 | F | Antiparasitic activity against Cryptosporidium parvum infection model | Cryptosporidium parvum | 6 | organism-based format | Scientific Literature | ||
| 3. | ALA1960801 | F | Selectivity ratio of EC50 for wild type Toxoplasma gondii expressing endogenous IMPDH to EC50 for hypoxanthine-guanine-xanthine phosphoribosyltransferase gene knock out Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 5 | organism-based format | Scientific Literature | ||
| 4. | ALA1960802 | F | Antiparasitic activity against wild type Toxoplasma gondii expressing endogenous IMPDH infected in human foreskin fibroblasts assessed as inhibition of parasite proliferation by fluorescence assay | Toxoplasma gondii | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA1960803 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluorescence assay in presence of bovine serum albumin | Cryptosporidium parvum | 38 | assay format | Scientific Literature | ||
| 6. | ALA1960804 | B | Inhibition of human IMPDH2 | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 7. | ALA1960806 | B | Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluorescence assay | Cryptosporidium parvum | 38 | assay format | Scientific Literature | ||
| 8. | ALA3362456 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature | ||
| 9. | ALA3362457 | B | Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Cryptosporidium | 6 | single protein format | Scientific Literature | ||
| 10. | ALA3362471 | B | Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Cryptosporidium | 4 | single protein format | Scientific Literature | ||
| 11. | ALA3362472 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature |
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