| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1960455 | F | Bone strenthening activity in Sprague-Dawley rat bone fracture-healing model assessed as increase in strength of fractured fibulae bone at 300 ug/kg administered as topical injection with PLGA microsphere formulation for 17 days (Rvb = 56.9 %) | Rattus norvegicus | 1 | ALA1955856 | organism-based format | Scientific Literature | |
| 2. | ALA1960456 | F | Bone strenthening activity in Sprague-Dawley rat bone fracture-healing model assessed as increase in strength of fractured fibulae bone at 1000 ug/kg administered as topical injection with PLGA microsphere formulation for 17 days (Rvb = 56.9 %) | Rattus norvegicus | 1 | ALA1955856 | organism-based format | Scientific Literature | |
| 3. | ALA1960457 | F | Bone strenthening activity in Sprague-Dawley rat bone fracture-healing model assessed as increase in strength of fractured fibulae bone administered as topical injection with PLGA microsphere formulation for 17 days | Rattus norvegicus | 1 | ALA1955856 | organism-based format | Scientific Literature | |
| 4. | ALA1960458 | B | Ratio of EC50 for rat EP4 receptor to Ki for mouse EP4 receptor | 4 | ALA1955856 | assay format | Scientific Literature | ||
| 5. | ALA1960459 | B | Ratio of EC50 for rat EP2 receptor to Ki for mouse EP2 receptor | 4 | ALA1955856 | assay format | Scientific Literature | ||
| 6. | ALA1961330 | B | Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 22 | ALA1955856 | cell-based format | Scientific Literature | |
| 7. | ALA1961331 | B | Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 22 | ALA1955856 | cell-based format | Scientific Literature | |
| 8. | ALA1961332 | B | Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 22 | ALA1955856 | cell-based format | Scientific Literature | |
| 9. | ALA1961333 | B | Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 22 | ALA1955856 | cell-based format | Scientific Literature | |
| 10. | ALA1960893 | F | Agonist activity at rat EP2 receptor | Rattus norvegicus | 8 | ALA1955856 | assay format | Scientific Literature | |
| 11. | ALA1960894 | F | Agonist activity at rat EP4 receptor | Rattus norvegicus | 8 | ALA1955856 | assay format | Scientific Literature | |
| 12. | ALA1960895 | P | Drug release from PLGA microspheres in PBS buffer assessed as compound remaining at 100 ug/ml after 7 days by HPLC analysis | 1 | ALA1955856 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA1960896 | P | Drug release from PLGA microspheres in PBS buffer assessed as compound remaining at 100 ug/ml after 21 days by HPLC analysis | 1 | ALA1955856 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA1960897 | P | Drug release from PLGA microspheres in PBS buffer assessed as compound remaining at 100 ug/ml after 28 days by HPLC analysis | 1 | ALA1955856 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA1960898 | F | Bone strenthening activity in Sprague-Dawley rat bone fracture-healing model assessed as increase in strength of fractured fibulae bone at 30 ug/kg administered as topical injection with PLGA microsphere formulation for 17 days (Rvb = 56.9 %) | Rattus norvegicus | 1 | ALA1955856 | organism-based format | Scientific Literature | |
| 16. | ALA1960899 | F | Bone strenthening activity in Sprague-Dawley rat bone fracture-healing model assessed as increase in strength of fractured fibulae bone at 100 ug/kg administered as topical injection with PLGA microsphere formulation for 17 days (Rvb = 56.9 %) | Rattus norvegicus | 1 | ALA1955856 | organism-based format | Scientific Literature | |
| 17. | ALA2038097 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by scintillation counting | Mus musculus | 29 | ALA2034814 | cell-based format | Scientific Literature | |
| 18. | ALA2038098 | B | Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 29 | ALA2034814 | cell-based format | Scientific Literature | |
| 19. | ALA2038099 | B | Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 29 | ALA2034814 | cell-based format | Scientific Literature | |
| 20. | ALA2038100 | B | Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 29 | ALA2034814 | cell-based format | Scientific Literature |
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