# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1960748 | B | Inhibition of Dengue virus NS2B-NS3 protease using Abz-NleKRRS-3-(NO2)Y as substrate at 50 uM preincubated for 15 mins measured every sec for 15 mins by fluorimetric analysis | Dengue virus | 163 | assay format | Scientific Literature | ||
2. | ALA1960749 | B | Inhibition of bovine plasma thrombin using Boc-Val-Pro-Arg-AMC as substrate at 25 uM preincubated for 15 mins measured after 10 mins by fluorimetric assay | Bos taurus | 163 | single protein format | Scientific Literature | ||
3. | ALA1960750 | B | Inhibition of Escherichia coli MurA using PEP as substrate assessed as inorganic phosphate release at 25 uM preincubated for 10 mins measured after 60 mins by fluorimetric assay | Escherichia coli | 163 | assay format | Scientific Literature | ||
4. | ALA1960751 | B | Inhibition of Escherichia coli MetAP at 10 uM after 15 mins by fluorescence analysis | Escherichia coli | 163 | assay format | Scientific Literature | ||
5. | ALA3991966 | B | Inhibition of c-Myc/Max interaction in human HL60 cells assessed as cell growth inhibition after 5 days by trypan blue exclusion assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3991967 | B | Inhibition of c-Myc/Max interaction in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | protein format | Patent Bioactivity Data | ||
7. | ALA3991968 | A | Effect on absolute levels of c-Myc in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3991969 | A | Effect on absolute levels of Max in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3991970 | B | Inhibition of recombinant human His6 tagged c-Myc bHLH-LZ domain (353 to 439 residues) with GGCD extension at C-terminus/recombinant human full length His6 tagged Max (151 residues) expressed in Escherichia coli assessed as reduction of heterodimer binding to HEX labeled E-box-containing DNA after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 12 | assay format | Patent Bioactivity Data | ||
10. | ALA3991971 | B | Inhibition of human His6 tagged Max (160 residues) homodimer binding to HEX labeled E-box-containing DNA after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 12 | single protein format | Patent Bioactivity Data |