# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1959086 | Binding | Inhibition of rat liver Acetyl-CoA carboxylase 1 using acetyl-CoA as substrate preincubated for 10 mins prior substrate addition measured after 20 mins by luminescence counting | Rattus norvegicus | 27 | ALA1955747 | assay format | Scientific Literature | |
2. | ALA1959087 | Binding | Inhibition of human Acetyl-CoA carboxylase 2 expressed in CHO cells after 1 hr by fluorescence assay | Homo sapiens | 28 | ALA1955747 | cell-based format | Scientific Literature | |
3. | ALA4234934 | Functional | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4229482 | cell-based format | Scientific Literature | |
4. | ALA4234935 | Functional | Antiproliferative activity against human SW620 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4229482 | cell-based format | Scientific Literature | |
5. | ALA4234936 | Functional | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4229482 | cell-based format | Scientific Literature | |
6. | ALA4234937 | Functional | Antiproliferative activity against human NCI-H1975 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4229482 | cell-based format | Scientific Literature | |
7. | ALA4234938 | Binding | Inhibition of C-terminal His-tagged full length human ACC2 expressed in Baculovirus infected Sf9 insect cells using acetyl CoA as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 21 | ALA4229482 | cell-based format | Scientific Literature | |
8. | ALA4234939 | Binding | Inhibition of C-terminal His-tagged recombinant human ACC1 (1 to 2383 residues) expressed in Baculovirus infected Sf9 insect cells using acetyl CoA as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-Glo assay | Homo sapiens | 21 | ALA4229482 | cell-based format | Scientific Literature | |
9. | ALA4234940 | Functional | Antiproliferative activity against human Caco2 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4229482 | cell-based format | Scientific Literature |