# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1964081 | F | PUBCHEM_BIOASSAY: S16 Schwann cell PMP22 intronic element firefly luciferase assay. (Class of assay: confirmatory) | 1,025 | cell-based format | PubChem BioAssays | |||
2. | ALA2394865 | A | Drug excretion in human urine after 24 hrs | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
3. | ALA2394866 | T | Toxicity in rat at 1600 mg/kg, po up to 120 mins | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2394867 | A | Half life in rat liver microsomes | Rattus norvegicus | 36 | microsome format | Scientific Literature | ||
5. | ALA2395030 | A | Ratio of drug level in brain to plasma in rat at 1600 mg/kg, po after 120 mins | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
6. | ALA2395031 | A | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in MDR1 transfected dog MDCK cells | Canis lupus familiaris | 36 | cell-based format | Scientific Literature | ||
7. | ALA2395032 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | Not specified | 1 | assay format | Scientific Literature | ||
8. | ALA2395033 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 100 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | Not specified | 33 | assay format | Scientific Literature | ||
9. | ALA2395034 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 10 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | Not specified | 36 | assay format | Scientific Literature | ||
10. | ALA2395035 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed as peroxide-induced cell death at 1 uM incubated 30 mins prior to peroxide challenge measured after 24 hrs by LDH release assay | Not specified | 36 | assay format | Scientific Literature | ||
11. | ALA2395036 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 100 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | Not specified | 32 | assay format | Scientific Literature | ||
12. | ALA2395037 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 10 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | Not specified | 36 | assay format | Scientific Literature | ||
13. | ALA2395038 | F | Neuroprotective activity in cortical neuron (unknown origin) assessed protection against glutamate-induced cell death at 1 uM incubated 30 mins prior to glutamate challenge measured after 24 hrs by LDH release assay | Not specified | 36 | assay format | Scientific Literature | ||
14. | ALA2395040 | A | Cytotoxicity against cortical neuron (unknown origin) at 10 uM | Not specified | 36 | assay format | Scientific Literature | ||
15. | ALA2395041 | B | Binding affinity to M5 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
16. | ALA2395042 | B | Binding affinity to M4 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
17. | ALA2395043 | B | Binding affinity to M2 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
18. | ALA2395044 | B | Binding affinity to M3 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
19. | ALA2395045 | B | Binding affinity to M1 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
20. | ALA2395046 | B | Selectivity ratio of IC50 for sigma2 receptor (unknown origin) to IC50 for sigma1 receptor (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature |