# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA766076 | B | Relative binding affinity to prealbumin was determined from the competition binding assays and is expressed relative to L-T4 | 18 | single protein format | Scientific Literature | |||
2. | ALA766078 | B | Concentration at which 50% total binding to prealbumin protein. | 4 | single protein format | Scientific Literature | |||
3. | ALA766079 | B | Displacement of [125I]thyroxin from human plasma prealbumin. | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
4. | ALA766080 | B | Thyroxine binding constant on human plasma prealbumin. | 9 | cell-free format | Scientific Literature | |||
5. | ALA763225 | B | Relative binding affinity for thyroxin binding prealbumin (TBPA) from rat liver compared to thyroxine (T4) as KA(comp)/KA(T4) | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
6. | ALA808442 | B | Relative binding affinity for nuclear receptor from rat liver compared to thyroxine (T4) as KA(comp)/KA(T4 | 11 | assay format | Scientific Literature | |||
7. | ALA846781 | B | KPCB/ K352 ratio of the compound | 9 | assay format | Scientific Literature | |||
8. | ALA872182 | B | Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) | Rattus norvegicus | 116 | assay format | Scientific Literature | ||
9. | ALA3090350 | B | Inhibition of human recombinant TTR Y78F mutant-mediated fibrillogenesis at 40 uM after 30 mins by turbidimetric assay relative to control | Homo sapiens | 21 | assay format | Scientific Literature | ||
10. | ALA3090351 | B | Inhibition of human recombinant TTR Y78F mutant-mediated fibrillogenesis after 30 mins by turbidimetric assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
11. | ALA3862350 | B | Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuring turbidity preincubated for 30 mins followed by lowering pH from 7.2 to 4.4 measured after 72 hrs by microplate spectrophotometric method | Homo sapiens | 6 | assay format | Scientific Literature | ||
12. | ALA3862360 | T | Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 72 hrs by resazurin reduction assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4055896 | B | Inhibition of acid-induced wild type transthyretin (unknown origin) aggregation expressed in Escherichia coli pre-incubated for 30 mins before acid addition and further incubated for 72 hrs at 37 degC under dark conditions by UV-Vis spectrophotometry | Homo sapiens | 289 | assay format | Scientific Literature | ||
14. | ALA4055897 | B | Binding affinity to transthyretin in human blood plasma assessed as plasma binding selectivity by measuring stoichiometry of small molecule bound to TTR incubated for 24 hrs at 37 degC by RP-HPLC | Homo sapiens | 288 | single protein format | Scientific Literature |