| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA645211 | B | Displacement of [3H]clonidine from rat cortex membrane Alpha-2 adrenergic receptors | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 2. | ALA698300 | B | Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand) | Oryctolagus cuniculus | 119 | assay format | Scientific Literature | ||
| 3. | ALA841027 | B | Displacement of [125I]p-iodoclonidine from imidazoline receptor I-1 in rat pheochromocytoma cells | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA842748 | B | Displacement of [3H]idazoxan from imidazoline receptor I-2 of rabbit kidney membranes | Oryctolagus cuniculus | 13 | assay format | Scientific Literature | ||
| 5. | ALA842305 | B | Binding affinity for rat imidazoline I2 receptor from crude P2 membranes; 1-5 | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 6. | ALA845131 | B | Relative binding to imidazoline I1 and alpha-2 adrenergic receptors (ratio of pKi) | 13 | assay format | Scientific Literature | |||
| 7. | ALA845132 | B | Relative binding to imidazoline I1 and imidazoline I2 binding sites (ratio of pKi) | 13 | assay format | Scientific Literature | |||
| 8. | ALA663587 | B | Relative binding to imidazoline I2 and alpha-2 adrenergic receptors (ratio of pKi) | 13 | assay format | Scientific Literature | |||
| 9. | ALA717307 | B | Relative binding to imidazoline I2 and imidazoline I1 binding sites (ratio of pKi) | 13 | assay format | Scientific Literature | |||
| 10. | ALA1959317 | B | Binding affinity to I2 imidazoline binding site | 2 | assay format | Scientific Literature | |||
| 11. | ALA1959318 | B | Selectivity ratio of I2 imidazoline binding site to alpha2 adrenergic receptor | 1 | assay format | Scientific Literature | |||
| 12. | ALA973552 | B | Displacement of [3H]2-BFI from Imidazoline receptor 2 in Sprague-Dawley rat whole brain membrane | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
| 13. | ALA973553 | B | Displacement of [3H]RX821002 from Adrenergic alpha2 receptor in Sprague-Dawley rat whole brain membrane | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
| 14. | ALA973554 | B | Selectivity ratio, IC50 for Imidazoline receptor 1 in Sprague-Dawley rat kidney membrane to Ki for Imidazoline receptor 2 in Sprague-Dawley rat whole brain membrane | Rattus norvegicus | 12 | cell membrane format | Scientific Literature | ||
| 15. | ALA973555 | B | Selectivity ratio, IC50 for Imidazoline receptor 1 in Sprague-Dawley rat kidney membrane to Ki for alpha2 adrenoceptor in Sprague-Dawley rat whole brain membrane | Rattus norvegicus | 12 | cell membrane format | Scientific Literature | ||
| 16. | ALA973556 | B | Displacement of [3H]clonidine from Imidazoline receptor 1 rat PC-12 cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA973557 | B | Binding affinity to Imidazoline receptor 2 | 2 | assay format | Scientific Literature | |||
| 18. | ALA973558 | B | Selectivity ratio, pKi for Imidazoline receptor 2 to pKi for Imidazoline receptor 1 | 2 | assay format | Scientific Literature | |||
| 19. | ALA973559 | B | Selectivity ratio, pKi for Imidazoline receptor 2 to pKi for alpha2 adrenoceptor | 2 | assay format | Scientific Literature | |||
| 20. | ALA973561 | F | Increase in morphine-induced analgesia in CD1 mouse at 10 mg/kg, sc after 30 mins by tail flick test relative to control | Mus musculus | 6 | organism-based format | Scientific Literature |
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