# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA911221 | B | Inhibition of bovine erythrocyte AChE | Bos taurus | 22 | single protein format | Scientific Literature | ||
2. | ALA3238626 | B | Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
3. | ALA3238627 | B | Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
4. | ALA3238628 | B | Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr by FRET assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
5. | ALA3238630 | B | Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate at 5 uM preincubated for 1 hr by FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA3238631 | B | Inhibition of human recombinant AChE-mediated amyloid beta-40 aggregation assessed as amyloid fibril formation at 100 uM after 24 hrs by thioflavin T fluorescence method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
7. | ALA3238632 | B | Inhibition of amyloid beta-42 (unknown origin) aggregation assessed as amyloid fibril formation at 10 uM after 24 hrs by thioflavin T fluorescence method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
8. | ALA3238633 | P | Permeability of the compound by PAMPA assay | 14 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA5161345 | B | Inhibition of recombinant human sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 mins for by fluorescence based assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
10. | ALA5161346 | B | Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured every 240 sec by Ellman's method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
11. | ALA5161347 | B | Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured every 240 sec by Ellman's method | Homo sapiens | 8 | single protein format | Scientific Literature | ||
12. | ALA5161348 | B | Inhibition of recombinant mouse sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 mins for by fluorescence based assay | Mus musculus | 9 | single protein format | Scientific Literature | ||
13. | ALA5161349 | B | Inhibition of recombinant mouse AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured every 240 sec by Ellman's method | Mus musculus | 9 | single protein format | Scientific Literature |