# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2016026 | B | Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weaver Burk plot | Homo sapiens | 10 | assay format | Scientific Literature | ||
2. | ALA2016027 | B | Competitive inhibition of GST-tagged human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weaver Burk plot | Homo sapiens | 10 | assay format | Scientific Literature | ||
3. | ALA2016028 | B | Competitive inhibition of GST-tagged human recombinant LMW-PTP IF2 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weaver Burk plot | Homo sapiens | 10 | assay format | Scientific Literature | ||
4. | ALA2016029 | B | Competitive inhibition of human recombinant TCPTP using p-nitrophenylphosphate as substrate by Line-Weaver Burk plot | Homo sapiens | 10 | single protein format | Scientific Literature | ||
5. | ALA2016030 | B | Selectivity ratio of IC50 for human recombinant LMW-PTP IF2 to IC50 for human recombinant LMW-PTP IF1 | Homo sapiens | 10 | assay format | Scientific Literature | ||
6. | ALA2016031 | B | Selectivity ratio of IC50 for human recombinant TCPTP to IC50 for human recombinant PTP1B | Homo sapiens | 10 | assay format | Scientific Literature | ||
7. | ALA2016032 | A | Cytotoxicity against mouse C2C12 cells at 25 uM after 2 hrs by MTT assay | Mus musculus | 10 | cell-based format | Scientific Literature | ||
8. | ALA2016033 | B | Inhibition of PTP1B in mouse C2C12 cells assessed as increase in insulin receptor beta tyrosine phosphorylation at 25 uM | Mus musculus | 7 | cell-based format | Scientific Literature | ||
9. | ALA2016034 | B | Inhibition of PTP1B in mouse C2C12 cells assessed as increase in intracellular 2-deoxyglucose uptake using [3H]glucose as substrate at 25 uM after 90 mins by scintillation counting | Mus musculus | 8 | cell-based format | Scientific Literature |