| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2013321 | B | Inhibition of human recombinant DDX3 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in to single stranded nucleic acid by laser scanning densitometric analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 2. | ALA2013322 | B | Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in to single stranded nucleic acid by laser scanning densitometric analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 3. | ALA2013323 | B | Inhibition of Hepatitis C virus NS3 helicase expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in to single stranded nucleic acid by laser scanning densitometric analysis | Hepatitis C virus | 7 | assay format | Scientific Literature | ||
| 4. | ALA2013324 | B | Inhibition of human recombinant DDX3 ATPase activity expressed in Escherichia coli assessed as [gamma-32P] ATP hydrolysis after 5 mins by densitometric analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 5. | ALA2013325 | F | Antiviral activity against multidrug-resistant HIV1 infected in phytohemagglutininin-P stimulated human PBMC cells assessed as inhibition of viral replication after 72 hrs post infection | Human immunodeficiency virus 1 | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA2013326 | A | Cytotoxicity against human PBMC cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA2013327 | A | Selectivity ratio of CC50 for human PBMC cells to EC50 for multidrug-resistant HIV1 infected in phytohemagglutininin-P-stimulated human PBMC cells | 2 | cell-based format | Scientific Literature | |||
| 8. | ALA2013328 | B | Competitive inhibition of human recombinant DDX3 expressed in Escherichia coli using 25 nM double strand 18/36mer RNA substrate by PAGE analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA2013329 | B | Competitive inhibition of human recombinant DDX3 expressed in Escherichia coli using 50 nM double strand 18/36mer RNA substrate by PAGE analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA2013330 | B | Competitive inhibition of human recombinant DDX3 expressed in Escherichia coli using 100 nM double strand 18/36mer RNA substrate by PAGE analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5216452 | B | Inhibition of DDX3X (unknown origin) helicase activity | Homo sapiens | 11 | single protein format | Scientific Literature |
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