# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2014888 | F | Antiinflammatory activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced TNF-alpha production preincubated for 15 mins prior DNP-BSA challenge measured after 30 mins by ELISA | Rattus norvegicus | 6 | ALA2010773 | cell-based format | Scientific Literature | |
2. | ALA2411913 | B | Binding affinity to human UCH-L1 after 1 hr by SDS-PAGE analysis | Homo sapiens | 1 | ALA2406999 | single protein format | Scientific Literature | |
3. | ALA2411914 | B | Binding affinity to human USP4 after 1 hr by SDS-PAGE analysis | Homo sapiens | 1 | ALA2406999 | single protein format | Scientific Literature | |
4. | ALA2412073 | B | Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using K48-linked tetraubiquitin as substrate assessed as substrate hydrolysis at 5 to 50 uM after 15 mins by SDS-PAGE analysis | Homo sapiens | 1 | ALA2406999 | assay format | Scientific Literature | |
5. | ALA2412080 | B | Binding affinity to USP5 in rat RBL2H3 cell extracts at 1 to 100 uM by SDS-PAGE analysis | Rattus norvegicus | 1 | ALA2406999 | cell-based format | Scientific Literature | |
6. | ALA2412081 | B | Binding affinity to human recombinant USP5 by SDS-PAGE analysis | Homo sapiens | 2 | ALA2406999 | single protein format | Scientific Literature | |
7. | ALA4479671 | B | Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUMO1-AMC as substrate measured after 1 hr by fluorescence analysis | Homo sapiens | 5 | ALA4477251 | assay format | Scientific Literature | |
8. | ALA4479672 | B | Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition of SUMO1-AMC as substrate measured after 1 hr by fluorescence analysis | Homo sapiens | 5 | ALA4477251 | assay format | Scientific Literature |