| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2019530 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 2. | ALA2019531 | B | Inhibition of human recombinant UAE assessed as inhibition of UbcH6-Ub complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 3. | ALA2019532 | B | Inhibition of human recombinant SAE1/2 assessed as inhibition of SUMO1-UbcH9 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | protein complex format | Scientific Literature | ||
| 4. | ALA2019634 | B | Inhibition of human recombinant UBA5 assessed as inhibition of UCF1-UFM1 complex formation at 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 5. | ALA2019640 | B | Inhibition of UBA3-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis | 2 | single protein format | Scientific Literature | |||
| 6. | ALA2019641 | B | Inhibition of APPBP1-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis | 2 | single protein format | Scientific Literature | |||
| 7. | ALA2019652 | F | Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 8. | ALA2328927 | B | Inhibition of UBA7 (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2328928 | B | Inhibition of ATG7 (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2328929 | B | Inhibition of UBA6 (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2328930 | B | Inhibition of NAE (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA2328931 | B | Inhibition of SAE (unknown origin) in presence of ATP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA2328932 | B | Inhibition of UAE (unknown origin) in presence of ATP | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA2328933 | B | Inhibition of human UAE-catalyzed E1-E2 transthiolation reaction expressed in Sf9 insect cells after 90 mins by TR-FRET assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2328934 | B | Competitive inhibition of human UAE-catalyzed ATP-PPi exchange reaction expressed in Sf9 insect cells after 60 mins in presence of 1 uM ATP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2328935 | B | Competitive inhibition of human UAE-catalyzed ATP-PPi exchange reaction expressed in Sf9 insect cells after 60 mins in presence of 10 uM ATP | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3880799 | B | Inhibition of recombinant human untagged NAEalpha/N-terminal His-tagged NAEbeta expressed in Bac-to-Bac expression system using FLAG-tagged NEDD8 as substrate after 90 mins in presence of GST-tagged Ubc12 by HTRF assay | Homo sapiens | 123 | assay format | Patent Bioactivity Data | ||
| 18. | ALA5151020 | B | Inhibition of NAE (unknown origin) | Homo sapiens | 3 | protein complex format | Scientific Literature |
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