# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2019530 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | assay format | Scientific Literature | |
2. | ALA2019531 | B | Inhibition of human recombinant UAE assessed as inhibition of UbcH6-Ub complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | assay format | Scientific Literature | |
3. | ALA2019532 | B | Inhibition of human recombinant SAE1/2 assessed as inhibition of SUMO1-UbcH9 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | protein complex format | Scientific Literature | |
4. | ALA2019634 | B | Inhibition of human recombinant UBA5 assessed as inhibition of UCF1-UFM1 complex formation at 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | single protein format | Scientific Literature | |
5. | ALA2019635 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation after 1.5 hrs by Western blot analysis | Homo sapiens | 1 | ALA2016531 | assay format | Scientific Literature | |
6. | ALA2019636 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 1 nM after 1.5 hrs by Western blot analysis | Homo sapiens | 7 | ALA2016531 | assay format | Scientific Literature | |
7. | ALA2019640 | B | Inhibition of UBA3-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis | 2 | ALA2016531 | single protein format | Scientific Literature | ||
8. | ALA2019641 | B | Inhibition of APPBP1-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis | 2 | ALA2016531 | single protein format | Scientific Literature | ||
9. | ALA2019642 | B | Inhibition of ABL assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
10. | ALA2019643 | B | Inhibition of CAMK2b assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
11. | ALA2019644 | B | Inhibition of CDK1/cyclin B assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | protein complex format | Scientific Literature | ||
12. | ALA2019645 | B | Inhibition of DAPK1 assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
13. | ALA2019646 | B | Inhibition of EGFR assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
14. | ALA2019647 | B | Inhibition of IGF1R assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
15. | ALA2019648 | B | Inhibition of JAK1 assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
16. | ALA2019649 | B | Inhibition of JAK3 assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
17. | ALA2019650 | B | Inhibition of MEK1 assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
18. | ALA2019651 | B | Inhibition of TRKA assessed as remaining activity at 0.1 uM by radiolabeled kinase assay relative to control | 1 | ALA2016531 | single protein format | Scientific Literature | ||
19. | ALA2019652 | F | Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 17 | ALA2016531 | cell-based format | Scientific Literature | |
20. | ALA2019653 | B | Inhibition of NAE in human K562 cells assessed as inhibition of NEDD8-cullin complex formation at 1 to 1000 nM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA2016531 | cell-based format | Scientific Literature |